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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-1845</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>Осложненные формы первичного туберкулеза у детей и подростков</article-title><trans-title-group xml:lang="en"><trans-title>Complicated forms of primary tuberculosis in children and adolescents</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шепелева</surname><given-names>Л. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Shepeleva</surname><given-names>L. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шепелева Лариса Петровна – к.м.н., зав. отделением</p></bio><bio xml:lang="en"><p>Shepeleva Larisa Petrovna, Head of the Radiologic Diagnostics Department</p><p>PhD (Medicine)</p><p>677015, Sakha Republic (Yakutia), Yakutsk, 93 Petr Alexeev St., phone: +7(4112)35-03- 25, fax: +7(4112)47-50-80</p></bio><email xlink:type="simple">shepelevalp@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никифорова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikiforova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никифорова Нина Афанасьевна – врач рентгенолог отделения</p></bio><bio xml:lang="en"><p>Nikiforova Nina Afanasievna, radiologist of the Radiologic Diagnostics Department</p><p>677015, Sakha Republic (Yakutia), Yakutsk, 93 Petr Alexeev St., phone: +7(4112)35-03- 25, fax: +7(4112)47-50-80</p></bio><email xlink:type="simple">nikiada@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Научно-практический центр «Фтизиатрия»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>‘Phthisiatry’ Research &amp; Practice Center</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>04</day><month>10</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>115</fpage><lpage>118</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Шепелева Л.П., Никифорова Н.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Шепелева Л.П., Никифорова Н.А.</copyright-holder><copyright-holder xml:lang="en">Shepeleva L.P., Nikiforova N.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1845">https://ymj.elpub.ru/jour/article/view/1845</self-uri><abstract><p>В статье дан анализ осложненных форм первичного туберкулеза у детей и подростков на основе данных 45 больных, которые наблюдались и проходили лечение в НПЦ «Фтизиатрия» РС (Я). При этом выявлена зависимость клинико-рентгенологической особенности течения первичного туберкулезного процесса от возрастного фактора. Отмечено, что в силу особенностей возрастной реактивности в раннем и подростковом возрасте чаще встречается осложненное течение первичного туберкулеза в виде бронхолегочного поражения и генерализации процесса с вовлечением других органов и систем. В дошкольном и младшем школьном возрасте неблагоприятное течение туберкулеза является гораздо более редким исключением и чаще встречается в виде лимфогенных обсеменений.</p></abstract><trans-abstract xml:lang="en"><p>Analysis of complicated forms of pediatric primary tuberculosis is presented, based on x-ray findings of 45 patients, treated in the ‘Phthisiatry’ Research &amp; Practice Center, Sakha Republic (Yakutia). The study revealed that clinical x-ray pattern of primary tuberculosis complex correlated with age factor. We observed that due to age-specific host responsiveness differences, a complicated clinical progression of primary tuberculosis complex occurred more often in adolescents and infants, and manifested as bronchopulmonary involvement with generalization of the process spreading to other organs and systems. In preschool and junior school age, an unfavorable tuberculosis progression was far rarer exclusion and manifested predominantly as lymphogenous seeding.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>первичный туберкулез</kwd><kwd>осложнения</kwd><kwd>дети</kwd><kwd>подростки</kwd><kwd>компьютерная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>primary tuberculosis</kwd><kwd>complications</kwd><kwd>children</kwd><kwd>adolescents</kwd><kwd>computer tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Руководство по туберкулезу / под ред. А.Е. 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Brissaut // Pediatrics. –1960. – Vol. 26. – № 4. P. 641-653.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Tuberculosis in children younger than five years old / C. Driver, J. Luallen, W. Good [et al.] // Ped.Inf. Dis.J. – 1995. – Vol.14, – №2. – P.112-117.</mixed-citation><mixed-citation xml:lang="en">Tuberculosis in children younger than five years old / C. Driver, J. Luallen, W. Good [et al.] // Ped.Inf. Dis.J. – 1995. – Vol.14, – №2. – P.112-117.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
