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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-1839</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НАУЧНЫЕ ОБЗОРЫ И ЛЕКЦИИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>SCIENTIFIC REVIEWS AND LECTURES</subject></subj-group></article-categories><title-group><article-title>Качество жизни больных хронической обструктивной болезнью легких</article-title><trans-title-group xml:lang="en"><trans-title>Life quality of chronic obstructive pulmonary disease patients</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тимофеева</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Timofeeva</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тимофеева Александра Васильевна – к.м.н., с.н.с.</p></bio><bio xml:lang="en"><p>Timofeeva Aleksandra Vasilievna – PhD, IH</p><p>677710 Sergelyahcskoe higway 4 building C-2, Yakutsk, Tel: 89247605094</p></bio><email xlink:type="simple">TAV_76@inbox.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>НИИ здоровья СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>NEFU</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>04</day><month>10</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>100</fpage><lpage>103</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Тимофеева А.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Тимофеева А.В.</copyright-holder><copyright-holder xml:lang="en">Timofeeva A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1839">https://ymj.elpub.ru/jour/article/view/1839</self-uri><abstract><p>Анализ литературных данных свидетельствует о том, что хроническая обструктивная болезнь легких (ХОБЛ) приводит к ухудшению всех составляющих качества жизни пациента. Ограничения для нормальной жизни больных нарастают с утяжелением болезни. Вместе с тем имеются и другие данные относительно влияния тяжести болезни на качество жизни. Показана и значительная вариабельность показателей качества жизни в пределах одной степени тяжести. Противоречивы данные литературы о влиянии пола на качество жизни. Мало исследований о качестве жизни больных с разными степенями тяжести ХОБЛ, его динамике в процессе развития болезни. Лишь единичные исследования содержат данные о влиянии длительной базисной терапии на качество жизни пациентов с ХОБЛ.</p></abstract><trans-abstract xml:lang="en"><p>The analysis of the literary data testifies, that chronic obstructive pulmonary disease (COPD) leads to deterioration of all life quality components of the person. Restrictions for normal life of patients accrue with illness weighting. At the same time there is other data relative to influence of illness gravity on life quality. Appreciable variability of life quality indicators within one severity level was shown too. The literary data about sex influence on life quality are inconsistent. There are too little researches about life quality of patients with different severity level of COPD and its dynamics in illness development. Only individual researches contain the data about influence of long basic therapy on life quality of patients with COPD.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хроническая обструктивная болезнь легких</kwd><kwd>качество жизни</kwd><kwd>SF-36</kwd><kwd>SGRQ</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic obstructive pulmonary disease</kwd><kwd>quality of a life</kwd><kwd>SF-36</kwd><kwd>SGRQ</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Влияние тиотропия бромида на эффективность легочной реабилитации у больных хронической обструктивной болезнью легких / В.А. Игнатьев, О.Н. Титова, М.Д. Дидур [и др.] // Пульмонология. – 2007. – № 1. – С. 88–94.</mixed-citation><mixed-citation xml:lang="en">Tiotropium Bromidum influence on efficiency of pulmonary rehabilitation at patients with chronic obstructive pulmonary disease / V.A. Ignatyev, O.N. Titov, M.D. Didur [et al.] // Pulmonology. – 2007. – № 1. – P. 88–94.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Качество жизни больных хроническими обструктивными болезнями легких / Е.И. Шмелев, М.В. Беда, P.W. Jones [и др.] // Пульмонология. – 1998. – № 2. – С. 79–81.</mixed-citation><mixed-citation xml:lang="en">The life quality of patients with chronic obstructive pulmonary disease / E.I. Shmelev, M.V. Beda, P.W. Jones [et al.] // Pulmonology. - 1998. - № 2. - P. 79-81.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Качество жизни больных хронической обструктивной болезнью легких в России: результаты многоцентрового популяционного исследования «ИКАР-ХОБЛ» / А.Г. Чучалин, А.С. Белевский, Б.А. Черняк [и др.] // Пульмонология. – 2005. – № 1. – С. 93–102.</mixed-citation><mixed-citation xml:lang="en">The life quality of patients with chronic obstructive pulmonary disease in Russia: results of multicenter population research “IKAR-COPD” / A.G. Chuchalin, A.S. Belevsky, B.A. Chernjak [et al.] // Pulmonology. – 2005. – № 1. – P. 93–102.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Качество жизни у больных бронхиальной астмой и хронической обструктивной болезнью легких / под ред. А.Г. Чучалина. – М.: Атмосфера, 2004. – 256 c.</mixed-citation><mixed-citation xml:lang="en">The life quality of patients with a bronchial asthma and chronic obstructive pulmonary disease / Under the editorship of A.G. Chuchalin – М: Atmosphere, 2004. – 256 p.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Суховская О.А. Исследование качества жизни при заболеваниях органов дыхания / О.А. Суховская, М.М. Илькович, В.А. Игнатьев // Пульмонология. – 2003. – № 3. – С. 96–100.</mixed-citation><mixed-citation xml:lang="en">Suhovskyа, O.A. Life quality research at diseases of respiratory apparatus / O.A. Suhovsky,а M.M. Ilkovich, V.A. Ignatyev // Pulmonology. – 2003. – № 3. - P. 96–100.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Трофименко И.Н. Взаимосвязь клиникофункционального статуса и качества жизни у больных хронической обструктивной болезнью легких / И.Н. Трофименко, Б.А. Черняк // Сибирский консилиум. – 2008. – № 1. – С. 48–52.</mixed-citation><mixed-citation xml:lang="en">Trofimenko I.N. Interrelation of the clinicofunctional status and the life quality at patients with chronic obstructive pulmonary disease / I.N. Trofimenko, B.A. Chernjak // The Siberian consultation. – 2008. – № 1. – P. 48–52.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">A self-complete measure for chronic airflow limitation: The St. George´s Respiratory Questionnaire / P.W. Jones, F.H. Quirk, C.M. Baveystock [et al.] // Am. Rev. Respir. Dis. – 1992. – V. 145. – P. 1321–1327.</mixed-citation><mixed-citation xml:lang="en">A self-complete measure for chronic airflow limitation: The St. George´s Respiratory Questionnaire / P.W. Jones, F.H. Quirk, C.M. Baveystock [et al.] // Am. Rev. Respir. Dis. – 1992. – V. 145. – P. 1321–1327.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Analysis of the factors related to mortality in chronic obstructive pulmonary disease: role of exercise capacity and health status / T. Oga, K. Nishimura, M. Tsukino [et al.] // Am. J. Respir. Crit. Care Med. – 2003. – V. 167. – P. 544–549.</mixed-citation><mixed-citation xml:lang="en">Analysis of the factors related to mortality in chronic obstructive pulmonary disease: role of exercise capacity and health status / T. Oga, K. Nishimura, M. Tsukino [et al.] // Am. J. Respir. Crit. Care Med. – 2003. – V. 167. – P. 544–549.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Chronic obstructive pulmonary disease stage and health-related quality of life. The Quality of Life of Chronic Obstructive Pulmonary Disease Study Group / M. Ferrer, J. Alonso, J. Morera [et al.] // An. Int. Med. – 1997. – V. 127. – P. 1072–1079.</mixed-citation><mixed-citation xml:lang="en">Chronic obstructive pulmonary disease stage and health-related quality of life. The Quality of Life of Chronic Obstructive Pulmonary Disease Study Group / M. Ferrer, J. Alonso, J. Morera [et al.] // An. Int. Med. – 1997. – V. 127. – P. 1072–1079.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Do GOLD stages of COPD severity really correspond to differences in health status / R. Antonelli-Incalzi, C. Imperiale, V. Bellia [et al.] // Eur. Respir. J. – 2003. – V. 22. – P. 444–449.</mixed-citation><mixed-citation xml:lang="en">Do GOLD stages of COPD severity really correspond to differences in health status / R. Antonelli-Incalzi, C. Imperiale, V. Bellia [et al.] // Eur. Respir. J. – 2003. – V. 22. – P. 444–449.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Elevated CRP mark metabolic and functional impairment in advanced COPD / R. Broekhuizen, E.F. Wouters, E.C. Creutzberg [et al.] // Thorax. – 2006. – V. 61. – P. 17–22.</mixed-citation><mixed-citation xml:lang="en">Elevated CRP mark metabolic and functional impairment in advanced COPD / R. Broekhuizen, E.F. Wouters, E.C. Creutzberg [et al.] // Thorax. – 2006. – V. 61. – P. 17–22.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Health status deterioration in patients with chronic obstructive pulmonary disease / S. Spencer, P.M.A. Calverley, P.S. Burge [et al.] // Am. J. Respir. Crit. Care Med. – 2001. – V. 163. – P. 122–128.</mixed-citation><mixed-citation xml:lang="en">Health status deterioration in patients with chronic obstructive pulmonary disease / S. Spencer, P.M.A. Calverley, P.S. Burge [et al.] // Am. J. Respir. Crit. Care Med. – 2001. – V. 163. – P. 122–128.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Health-related quality of life and mortality in male patients with chronic obstructive pulmonary disease / A. Domingo-Salvany, R. Lamarca, M. Ferrer [et al.] // Am. J. Respir. Crit. Care Med. – 2002. – V. 166. – P. 680–685.</mixed-citation><mixed-citation xml:lang="en">Health-related quality of life and mortality in male patients with chronic obstructive pulmonary disease / A. Domingo-Salvany, R. Lamarca, M. Ferrer [et al.] // Am. J. Respir. Crit. Care Med. – 2002. – V. 166. – P. 680–685.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Health-related quality of life in COPD: why both disease-specific and generic measures should be used / C.P. Engström, L.O. Persson, S. Laesson [et al.] // Eur. Respir. J. – 2001. – V. 18. – P. 69–76.</mixed-citation><mixed-citation xml:lang="en">Health-related quality of life in COPD: why both disease-specific and generic measures should be used / C.P. Engström, L.O. Persson, S. Laesson [et al.] // Eur. Respir. J. – 2001. – V. 18. – P. 69–76.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Health-related quality of life is related to COPD disease severity [Электронный ресурс] / E. Stahl, A. Lindberg, S-A. Jansson [et al.] // Health Qual. Life Outcomes. – 2005. – V. 3. – Электрон. дан. – Режим доступа: http://www.pubmedcentral.gov/redirect3.org.</mixed-citation><mixed-citation xml:lang="en">Health-related quality of life is related to COPD disease severity [Электронный ресурс] / E. Stahl, A. Lindberg, S-A. Jansson [et al.] // Health Qual. Life Outcomes. – 2005. – V. 3. – Электрон. дан. – Режим доступа: http://www.pubmedcentral.gov/redirect3.org.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Impact of preventing exacerbations on deterioration of health status in COPD / S. Spencer, P.M. Calverley, P.S. Burge [et al.] // Eur. Respir. J. – 2004. – V. 23. – P. 698–702.</mixed-citation><mixed-citation xml:lang="en">Impact of preventing exacerbations on deterioration of health status in COPD / S. Spencer, P.M. Calverley, P.S. Burge [et al.] // Eur. Respir. J. – 2004. – V. 23. – P. 698–702.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Jones P.W. St. George´s Respiratory Questionnaire: development, interpretation and use / P.W. Jones // Eur. Respir. Rev. – 2002. – V. 12. – P. 63–64.</mixed-citation><mixed-citation xml:lang="en">Jones P.W. St. George´s Respiratory Questionnaire: development, interpretation and use / P.W. Jones // Eur. Respir. Rev. – 2002. – V. 12. – P. 63–64.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Leidy N.K. An overview of health-related quality of life effects and outcomes in patients with COPD / N.K. Leidy, S.F. Anton, R.A. Berzon // Eur. Respir. Rev. – 2002. – V. 12. – P. 61–62.</mixed-citation><mixed-citation xml:lang="en">Leidy N.K. An overview of health-related quality of life effects and outcomes in patients with COPD / N.K. Leidy, S.F. Anton, R.A. Berzon // Eur. Respir. Rev. – 2002. – V. 12. – P. 61–62.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Longitudinal deteriorations in patients reported outcomes in patients with COPD / T. Oga, K. Nishimura, M. Tsukino [et al.] // Respir. Med. 2007. – V. 101. – P. 146–153.</mixed-citation><mixed-citation xml:lang="en">Longitudinal deteriorations in patients reported outcomes in patients with COPD / T. Oga, K. Nishimura, M. Tsukino [et al.] // Respir. Med. 2007. – V. 101. – P. 146–153.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Mortality after hospitalization for COPD / P. Almagro, E. Calbo, A.O. de Echaguen [et al.] // Chest. – 2002. – V. 121. – P. 1441–1448.</mixed-citation><mixed-citation xml:lang="en">Mortality after hospitalization for COPD / P. Almagro, E. Calbo, A.O. de Echaguen [et al.] // Chest. – 2002. – V. 121. – P. 1441–1448.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Outcomes for COPD pharmacological trials: from lung function to biomarkers / M. Cazzola, W. MacNee, F.J. Martinez [et al.] // Eur. Respir. J. – 2008. – V. 31. – P. 416–469.</mixed-citation><mixed-citation xml:lang="en">Outcomes for COPD pharmacological trials: from lung function to biomarkers / M. Cazzola, W. MacNee, F.J. Martinez [et al.] // Eur. Respir. J. – 2008. – V. 31. – P. 416–469.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Quality of life and hospital re-admission in patients with chronic obstructive pulmonary disease / I.M. Osman, D.J. Godden, J.A. Friend [et al.] // Thorax. – 1997. – V. 52. – P. 67–71.</mixed-citation><mixed-citation xml:lang="en">Quality of life and hospital re-admission in patients with chronic obstructive pulmonary disease / I.M. Osman, D.J. Godden, J.A. Friend [et al.] // Thorax. – 1997. – V. 52. – P. 67–71.</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">Sherbourne C.D, Stewart A.L., Wells K.B. Role functioning measures. In: Stewart A.L., Ware J.E. [et al.]. Measuring functioning and wellbeing: The Medical Outcomes Study Approach. – Durham, NC: Duke University Press., 1992. – P. 205–208.</mixed-citation><mixed-citation xml:lang="en">Sherbourne C.D, Stewart A.L., Wells K.B. Role functioning measures. In: Stewart A.L., Ware J.E. [et al.]. Measuring functioning and wellbeing: The Medical Outcomes Study Approach. – Durham, NC: Duke University Press., 1992. – P. 205–208.</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Spencer S. Time course of recovery of health status following an infective exacerbation of chronic bronchitis / S. Spencer, P.W. Jones // Thorax. – 2003. – V. – 58. – P. 589–593.</mixed-citation><mixed-citation xml:lang="en">Spencer S. Time course of recovery of health status following an infective exacerbation of chronic bronchitis / S. Spencer, P.W. Jones // Thorax. – 2003. – V. – 58. – P. 589–593.</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease / B.R. Celli, C.G. Cote, J.M. Marin [et al.] // N. Engl. J. Med. – 2004. – V. 350. – P. 1005–1012.</mixed-citation><mixed-citation xml:lang="en">The Body-Mass Index, Airflow Obstruction, Dyspnea, and Exercise Capacity Index in Chronic Obstructive Pulmonary Disease / B.R. Celli, C.G. Cote, J.M. Marin [et al.] // N. Engl. J. Med. – 2004. – V. 350. – P. 1005–1012.</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">The influence of COPD on health-related quality of life independent of the influence of comorbidity / J.G. van Manen, P.J. Bindels, F.W. Dekker [et al.] // J. Clin. Epidemiol. – 2003. – V.56. – P. 1177–1184.</mixed-citation><mixed-citation xml:lang="en">The influence of COPD on health-related quality of life independent of the influence of comorbidity / J.G. van Manen, P.J. Bindels, F.W. Dekker [et al.] // J. Clin. Epidemiol. – 2003. – V.56. – P. 1177–1184.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
