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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.1234/YMJ.2022.77.32</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-173</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>Зрительно-образная и семантическая память при болезни Паркинсона: анализ клинических случаев</article-title><trans-title-group xml:lang="en"><trans-title>Visual and semantic memory for Parkinson’s disease: clinical case analysis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2421-3652</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никишина</surname><given-names>В. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikishina</surname><given-names>V. B.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никишина Вера Борисовна – д.псих.н., проф.</p><p>Москва</p></bio><bio xml:lang="en"><p>Vera B. Nikishina – Grand PhD in Psychology, prof.</p><p>Moscow</p></bio><email xlink:type="simple">vbnikishina@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-3177-088X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петраш</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrash</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петраш Екатерина Анатольевна – д.псих.н., доцент, проф.</p><p>Москва</p></bio><bio xml:lang="en"><p>Ekaterina A. Petrash – Grand PhD in Psychology, associate Professor, prof.</p><p>Moscow</p></bio><email xlink:type="simple">petrash@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9781-6169</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шутеева</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Shuteeva</surname><given-names>E. Yu.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шутеева Елена Юрьевна – студентка КГМУ.</p><p>Курск</p></bio><bio xml:lang="en"><p>Elena Yu. Shuteeva – student of KSMU.</p><p>Kursk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-6465-4842</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шарашкина</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Sharashkina</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Шарашкина Наталья Викторовна – к.м.н., доцент, зав. отд. РГНКЦ.</p><p>Москва</p></bio><bio xml:lang="en"><p>Natalia V. Sharashkina – Candidate of Medical Sciences, Associate Professor, Head of Department, Pirogov Russian National Research Medical University.</p><p>Moscow</p></bio><email xlink:type="simple">sharashkina@inbox.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-2299-1952</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Захарова</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Zakharova</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Захарова Ирина Александровна – ассистент.</p><p>Москва</p></bio><bio xml:lang="en"><p>Irina Z. Zakharova – assistant.</p><p>Moscow</p></bio><email xlink:type="simple">anwiw@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГАОУ ВО РНИМУ им. Н.И. Пирогова Минздрава России</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University of the Ministry of Health of Russia</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>КГМУ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>KSMU</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>РГНКЦ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pirogov Russian National Research Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>05</day><month>02</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>125</fpage><lpage>132</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Никишина В.Б., Петраш Е.А., Шутеева Е.Ю., Шарашкина Н.В., Захарова И.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Никишина В.Б., Петраш Е.А., Шутеева Е.Ю., Шарашкина Н.В., Захарова И.А.</copyright-holder><copyright-holder xml:lang="en">Nikishina V.B., Petrash E.A., Shuteeva E.Y., Sharashkina N.V., Zakharova I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/173">https://ymj.elpub.ru/jour/article/view/173</self-uri><abstract><p>Целью работы является конкретизация механизмов трансформации содержания, подлежащего запоминанию, в процессе консолидации и реконсолидации у пациентов с болезнью Паркинсона (БП).</p><p>Наличие нейродегенеративных изменений вследствие патологического процесса при БП достоверно изменяет качество (объем и точность) извлекаемой информации или приводит к ее полной потере. У пациентов вне зависимости от формы заболевания (дрожательная, акинетико-ригидная или смешанная) консолидируется значимо меньший объем информации (как слухоречевой, так и зрительно-образной). Данная тенденция является соотносимой с выраженным искажением в процессе извлечения информации.</p></abstract><trans-abstract xml:lang="en"><p>The aim of the work is to specify the mechanisms of transformation of the content to be memorized in the process of consolidation and reconsolidation in patients with Parkinson's disease (PD).</p><sec><title>Materials and methods</title><p>Materials and methods. The study involved three patients with PD (disease duration no more than three years; second stage) without cognitive impairment with mixed (akinetic-rigid-tremor), akinetic-rigid and tremulous forms of the disease. When studying the processes of consolidation-reconsolidation of visual-figurative and semantic memory in PD patients, a symbolic image and a text from the epic of the Indians of Canada were proposed as a stimulating material for memorization. The study of the processes of consolidation-reconsolidation was carried out sequentially: direct reproduction after presentation, reproduction after 40 minutes, after 4 hours, after 36 hours.</p></sec><sec><title>Results</title><p>Results. When extracting visual-shaped information already at the stage of copying (storing information), a tendency appears to transform the symbol into a specific image ("bird", "owl"), which increases from stage to stage. As a result, there are not only distortions of the reproduced information up to its complete loss, but also simplification. The number of image details decreases, the accuracy of their reproduction decreases, and new elements that are absent in the original image are drawn. When the semantic content was reproduced immediately after presentation, the content loss was 25-27%. When playing text content after 40 minutes, the loss of semantic units was 50-52%. After 4 hours, the patients were able to reproduce 22-25% of the semantic content of the heard text. Revealed the suppression of verbal information in PD.</p></sec><sec><title>Conclusion</title><p>Conclusion. The presence of neurodegenerative changes due to a pathological process in PD significantly changes the quality (volume and accuracy) of the information retrieved or leads to its complete loss. In patients, regardless of the form of the disease (trembling, akinetic-rigid or mixed), a significantly smaller amount of information (both auditory-verbal and visual-shaped) is consolidated. This tendency is correlated with a pronounced distortion in the process of information extraction.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>зрительно-образная память</kwd><kwd>семантическая память</kwd><kwd>консолидация</kwd><kwd>реконсолидация</kwd><kwd>болезнь Паркинсона</kwd></kwd-group><kwd-group xml:lang="en"><kwd>visual-shaped memory</kwd><kwd>semantic memory</kwd><kwd>consolidation</kwd><kwd>reconsolidation</kwd><kwd>Parkinson's disease</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Величковский Б.Б. Рабочая память человека: Структура и механизмы / Б.Б. Величковский. - М: Когито-центр, 2015. - 247 с.</mixed-citation><mixed-citation xml:lang="en">Velichkovsky V. B. Human working memory: structure and mechanisms. 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