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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-1726</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Влияние коморбидности на исходы у больных острым коронарным синдромом с подъемом сегмента ST</article-title><trans-title-group xml:lang="en"><trans-title>Effect of comorbidity on outcome in acute coronary syndrome patients with ST segment elevation</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Морозова Елена Александровна – врач терапевт</p></bio><bio xml:lang="en"><p>Physician</p><p>Yakutsk, Republic Sakha (Yakutia)</p></bio><email xlink:type="simple">Dea2003@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Морозов</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Morozov</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Морозов Сергей Николаевич – к.м.н., докторант кафедры терапии, фармакологии с курсом скорой помощи</p></bio><bio xml:lang="en"><p>main specialist on health care of the Far Eastern Federal district</p></bio><email xlink:type="simple">mnmnmn1@rambler.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Донская</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Donskaya</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Донская Ариадна Андреевна – д.м.н., проф., зав. курсом ОВП ИПОВ</p></bio><bio xml:lang="en"><p>M.D., prof., manager by a course OVP IPOV</p><p>Yakutsk, Republic Sakha (Yakutia)</p></bio><email xlink:type="simple">Aradon1@yandex.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лоскутова</surname><given-names>К. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Loskutova</surname><given-names>K. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лоскутова Кюнняй Саввична – к.м.н., с.н.с.</p></bio><bio xml:lang="en"><p>main scientific specialist</p><p>Yakutsk, Republic Sakha (Yakutia)</p></bio><email xlink:type="simple">loscutovaks@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУ Якутская городская клиническая больница</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Yakutsk city hospital</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Московский государственный медико-стоматологический университет</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Moscow State University of Medicine and Dentistry;&#13;
Minzdrav RF</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>NEFU named after M.K. Ammosov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ЯНЦ КМП СО РАМН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>YSC SB RAMS</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2013</year></pub-date><pub-date pub-type="epub"><day>27</day><month>09</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>19</fpage><lpage>22</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Морозова Е.А., Морозов С.Н., Донская А.А., Лоскутова К.С., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Морозова Е.А., Морозов С.Н., Донская А.А., Лоскутова К.С.</copyright-holder><copyright-holder xml:lang="en">Morozova E.A., Morozov S.N., Donskaya A.A., Loskutova K.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1726">https://ymj.elpub.ru/jour/article/view/1726</self-uri><abstract><p>Проводилось исследование влияния коморбидной патологии на исходы у больных с диагнозом острый коронарный синдром с подъемом сегмента ST (OKCnST). Коморбидность регистрировалась у 88% обследованных. Наиболее часто из сопутствующих заболеваний встречаются обострение хронического холецистопанкреатита, эрозивно-язвенное поражение верхних отделов желудочно-кишечного тракта, хронический колит. Результаты статистического анализа показали значимое повышение частоты летального исхода в группе больных OKCnST с обострением хронического пиелонефрита и с эрозивно-язвенным поражением верхних отделов ЖКТ.</p></abstract><trans-abstract xml:lang="en"><p>Investigation of influence of comorbid disease on outcomes in patients with acute coronary syndrome with ST segment elevation (ACSeST) was conducted. Comorbidity was recorded in 88% of patients. The most common comorbidities are the aggravation of chronic cholecystopancreatitis, erosive and ulcerative lesions of the upper gastrointestinal tract, chronic colitis. Statistical analysis showed a significant increase in the incidence of death in ACSeST patients with exacerbation of chronic pyelonephritis and with erosive and ulcerative lesions of the upper gastrointestinal tract.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>коморбидность</kwd><kwd>острый коронарный синдром с подъемом сегмента ST</kwd><kwd>эрозивно-язвенное поражение верхних отделов желудочно-кишечного тракта</kwd><kwd>хронический пиелонефрит</kwd><kwd>хронический колит</kwd></kwd-group><kwd-group xml:lang="en"><kwd>comorbidity</kwd><kwd>acute coronary syndrome with ST segment elevation</kwd><kwd>erosive and ulcerative lesions of the upper gastrointestinal tract</kwd><kwd>chronic pyelonephritis</kwd><kwd>chronic colitis</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Верткин A.Л. Врач и пациент. Монтекки и Капулетти современной медицины / A.Л. Верткин, А.С. 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