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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-1658</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXPERIENCE EXCHANGE</subject></subj-group></article-categories><title-group><article-title>Применение иммунокорригирующей терапии у детей с рецидивирующими бронхитами</article-title><trans-title-group xml:lang="en"><trans-title>The use of immunotherapy in children with recurrent bronchitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванова Ольга Николаевна – д.м.н, проф.</p></bio><bio xml:lang="en"><p>Ivanova Olga Nikolaevna, MD, professor</p><p>Yakutsk The Republic of Sakha (Yakutia)</p></bio><email xlink:type="simple">olgadoctor@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МИ СВФУ им М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-Eastern Federal University named after M. K. Ammosov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>20</day><month>09</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>89</fpage><lpage>90</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Иванова О.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Иванова О.Н.</copyright-holder><copyright-holder xml:lang="en">Ivanova O.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1658">https://ymj.elpub.ru/jour/article/view/1658</self-uri><abstract><p>Проведено исследование клинико-иммунологической эффективности препарата бронхо-ваксом в группе детей с рецидивирующими бронхитами. При анализе изменений иммунного статуса у детей с рецидивирующим бронхитом выявлены снижение показателей Т-клеточного звена и компонентов комплемента, содержания IFN-γ, FNO-ά, повышение уровня ЦИК. У обследованных детей с рецидивирующими бронхитами применялся препарат бронхо-ваксом. Терапия проводилась десятидневным курсом (1 капсула в день) в течение трех месяцев. В результате терапии препаратом бронхо-ваксом отмечены улучшение показателей иммунного статуса и отсутствие рецидивов бронхита в течение последующих 3 месяцев после проведенной терапии.</p></abstract><trans-abstract xml:lang="en"><p>Here is a study of the clinical and immunological efficacy of broncho-vaxom in the group of children with recurrent bronchitis. In the analysis of changes of the immune status in children with we recurrent bronchitis revealed the decline in T-cell component and components of complement, increased levels of CIK, a reduced level of IFN-γ FNO-ά. examined children with recurrent bronchitis medication used broncho-vaxom. The therapy was carried out ten-day course (1 capsule per day) for three months. As a result of drug therapy of broncho-vaxom marked improvement in immune status and the absence of recurrence of bronchitis for the next 3 months after the therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>бронхит</kwd><kwd>иммунный статус</kwd><kwd>иммунокоррекция</kwd><kwd>сенсибилизация</kwd><kwd>эффективность</kwd><kwd>цитокины</kwd><kwd>иммуноглобулины</kwd></kwd-group><kwd-group xml:lang="en"><kwd>bronchitis</kwd><kwd>immune status</kwd><kwd>immunocorrection</kwd><kwd>sensitization</kwd><kwd>efficiency</kwd><kwd>cytokines</kwd><kwd>immunoglobulins</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Болезни органов дыхания у детей / Под ред. С.В. Рачинского, В.К. Таточенко. – М.: Медицина, 1997. – 496 с.</mixed-citation><mixed-citation xml:lang="en">Diseases of the respiratory system in children/ ed. by S.V. Raczynski, V.K. 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