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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-1566</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>Врожденный сифилис в составе микстинфекции у ребенка одного месяца жизни</article-title><trans-title-group xml:lang="en"><trans-title>Congenital Syphilis in the Composition of the Mixed Infection in a Child One Month of Life</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аргунова</surname><given-names>Е. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Argunova</surname><given-names>E. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аргунова Елена Филипповна – доцент</p></bio><bio xml:lang="en"><p>Argunova Elena F. – associate Professor of Pediatrics and pediatric surgery</p><p>Yakutsk</p></bio><email xlink:type="simple">eargunova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексеева Саргылана Николаевна – доцент</p></bio><bio xml:lang="en"><p>Alekseeva Sargylana N. – associate Professor of Pediatrics and pediatric surgery</p><p>Yakutsk</p></bio><email xlink:type="simple">sargylanao@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванова Ольга Николаевна – проф.</p></bio><bio xml:lang="en"><p>Ivanova Olga N. - Professor of the Department of Pediatrics and pediatric surgery</p><p>Yakutsk</p></bio><email xlink:type="simple">olgadoctor@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кондратьева</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kondratieva</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кондратьева Саргылана Афанасьевна – зав. онкологич. отд.</p></bio><bio xml:lang="en"><p>Kondratieva Sargylana A. –head of the Oncology Department</p><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ядреева</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Adreeva</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ядреева Ольга Валерьевна – врач гематолог онкологич. отд.</p></bio><bio xml:lang="en"><p>Adreeva Olga V. – doctor of Oncology Department</p><p>Yakutsk</p></bio><email xlink:type="simple">gematologia@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Слепцова</surname><given-names>Н. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sleptsova</surname><given-names>N. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Слепцова Наталья Александровна – зам. гл. врача</p></bio><bio xml:lang="en"><p>Sleptsova Natalia A. – the Deputy Chief Physician</p><p>Yakutsk</p></bio><email xlink:type="simple">dgkib@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хрюкина</surname><given-names>Е. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Hrukina</surname><given-names>E. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Хрюкина Елена Викторовна – врач кишечного отд.</p></bio><bio xml:lang="en"><p>Hrukina Elena V. – doctor of Department</p><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сивцева</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sivtseva</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сивцева Айсена Алексеевна – студентка 6 курса</p></bio><bio xml:lang="en"><p>Sivtseva Aisena – the 6th year student</p></bio><email xlink:type="simple">gigoflikAIS@mail.ru</email><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Мединститут СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>MI NEFU</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ПЦ РБ №1-НЦМ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>RB No. 1 NCM</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Детская городская клинич. больница №2</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Children's Clinical Hospital №2</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ДГКБ №2</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Children's Clinical Hospital № 2</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Мединститут СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>NEFU MI Yakutsk</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2016</year></pub-date><pub-date pub-type="epub"><day>16</day><month>09</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>52</fpage><lpage>54</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аргунова Е.Ф., Алексеева С.Н., Иванова О.Н., Кондратьева С.А., Ядреева О.В., Слепцова Н.А., Хрюкина Е.В., Сивцева А.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Аргунова Е.Ф., Алексеева С.Н., Иванова О.Н., Кондратьева С.А., Ядреева О.В., Слепцова Н.А., Хрюкина Е.В., Сивцева А.А.</copyright-holder><copyright-holder xml:lang="en">Argunova E.F., Alekseeva S.N., Ivanova O.N., Kondratieva S.A., Adreeva O.V., Sleptsova N.A., Hrukina E.V., Sivtseva A.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1566">https://ymj.elpub.ru/jour/article/view/1566</self-uri><abstract><p>В статье приведен клинический пример раннего врожденного сифилиса у ребенка 1 месяца, прошедшего лечение в онкологическом отделении Педиатрического центра РБ № 1-НЦМ и Детской городской клинической больнице №2. Диагноз при поступлении: анемия тяжелой степени, тромбоцитопения, острый лейкоз, жалобы на высыпания по всему телу, желтушность кожных покровов, общую слабость. У ребенка констатирована врожденная микст-инфекция: ранний сифилис, цитомегаловирусная, герпес, хламидийная, миклоплазменная.Пациент осмотрен специалистами: неврологом, гематологом, дерматовенерологом. Дерматовенерологом рекомендовано лечение пенициллином в дозе 100 тыс. ед/кг/сут. Кроме этого, назначены внутривенно неоцитотек в возрастной дозе по схеме, иммуновенин в течение 3 дней. Также проводилась гемокомпонентная заместительная, симптоматическая терапия, вводился альбумин. На фоне такого лечения состояние ребенка улучшилось, температура нормализовалась, прибавил в весе.</p></abstract><trans-abstract xml:lang="en"><p>This article deals with the clinical case of early congenital syphilis in the 1 month child, admitted to the Oncology Department of the Pediatric center of Republican hospital №1 – National Center of Medicine and the Children’s City Hospital №2. Complaints on admission to the hospital were rashes all over the body, yellowness of the skin, general weakness. The child was diagnosed with a congenital mixed infection: early syphilis, cytomegalovirus, herpes, chlamydia, mikoplazma.The patient was examined by specialists: a neurologist, a hematologist and dermatologist. Dermatologist recommended treatment with penicillin in a dose 100 thousand kg/day, divided into 6 injections over 28 days. In addition, neocytotect intravenously in age dose according to the scheme, immunovenin within 3 days. Also there was conducted hemocomponent substitutional, symptomatic therapy and albumin. On the background of such treatment the child’s condition has improved, he has no longer a temperature, put on weight.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>сифилис</kwd><kwd>новорожденный</kwd><kwd>анемия</kwd><kwd>микоплазменная инфекция</kwd><kwd>хламидиоз</kwd><kwd>герпес</kwd><kwd>тромбоцитопения</kwd></kwd-group><kwd-group xml:lang="en"><kwd>syphilis</kwd><kwd>newborn</kwd><kwd>anemia</kwd><kwd>Mycoplasma infection</kwd><kwd>Chlamydia</kwd><kwd>herpes</kwd><kwd>thrombocytopenia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Заторская Н.Ф. Современная диагностика и лечение раннего врожденного сифилиса : дис. … канд. мед. наук / Н.Ф. Заторская. – М., 2011. – 91 с.</mixed-citation><mixed-citation xml:lang="en">Zatorskaya N.F. 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