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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2022.78.33</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-156</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>Клинический случай АНЦА-ассоциированного системного васкулита у ребенка саха девяти лет</article-title><trans-title-group xml:lang="en"><trans-title>A clinical case of ANCA-associated systemic vasculitis in a nine-yearold Sakha child</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванова Ольга Николаевна – д.м.н., проф.</p><p>г. Якутск</p></bio><bio xml:lang="en"><p>Ivanova Olga N. – Ph.D. in medical sciences, Professor, Department of Pediatrics and Pediatric Surgery</p></bio><email xlink:type="simple">olgadoctor@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аргунова</surname><given-names>В. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Argunova</surname><given-names>V. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>АргуноваВера Маична – зав. отд.</p><p>г. Якутск</p></bio><bio xml:lang="en"><p>Argunova Vera M. – Head of the Department</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Слепцова</surname><given-names>П. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Sleptsova</surname><given-names>P. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Слепцова Полина Андреевна – врач</p><p>г. Якутск</p></bio><bio xml:lang="en"><p>Sleptsova Polina A. – physician of the emergency department</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Афонская</surname><given-names>М. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Afonskaya</surname><given-names>M. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Афонская Марина Викторовна – врач</p><p>г. Якутск</p></bio><bio xml:lang="en"><p> Afonskaya Marina V. – physician at CRC Marina V. – physician at CRC</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иннокентьева</surname><given-names>С. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Innokentyeva</surname><given-names>S. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иннокентьева Саргылана Ильинична – врач</p><p>г. Якутск</p></bio><bio xml:lang="en"><p>Innokentyeva Sargylana I. – physician of CR</p></bio><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>И. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>I. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванова Ирина Семеновна – студентка 2 курса</p><p>г. Якутск</p></bio><bio xml:lang="en"><p>Ivanova Irina S. – 2nd year student</p></bio><xref ref-type="aff" rid="aff-6"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аргунова</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Argunova</surname><given-names>T. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аргунова Тамара Александровна – студентка 6 курса</p><p>г. Якутск</p></bio><bio xml:lang="en"><p>Argunova Tamara A. – 6th year student of the Department of Psychology</p></bio><xref ref-type="aff" rid="aff-7"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бурцева</surname><given-names>Т. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Burtseva</surname><given-names>T. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бурцева Татьяна Егоровна – д.м.н., проф., в.н.с.- зав. лаб.</p><p>г. Якутск</p></bio><bio xml:lang="en"><p>Burtseva Tatiana E. – Ph.D. in medical sciences, professor, Department of Pediatrics and Pediatric Surgery</p></bio><email xlink:type="simple">bourtsevat@yandex.ru</email><xref ref-type="aff" rid="aff-8"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колобова</surname><given-names>О. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolobova</surname><given-names>O. L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Колобова Оксана Леонидовна – к.м.н., доцент</p><p>г. Якутск</p></bio><bio xml:lang="en"><p>Kolobova Oksana L. – Ph.D. in medical sciences, associate professor, Department of Hospital Pediatrics</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чикова</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Chikova</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чикова Ирина Александровна – к.м.н., доцент</p><p>г. Якутск</p></bio><bio xml:lang="en"><p>Chikova Irina A. – Ph.D. in medical sciences, Associate Professor at the Department of Hospital Pediatrics</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сантимов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Santimov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сантимов Андрей Вячеславович – к.м.н., доцент</p><p>г. Якутск</p></bio><bio xml:lang="en"><p>Santimov Andrey V. – Ph.D. in medical sciences, Associate Professor at the Department of Pediatrics</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-9"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Костик</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kostik</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Костик Михаил Михайлович – д.м.н., проф.</p><p>г. Якутск</p></bio><bio xml:lang="en"><p>Kostik Mikhail M. – Ph.D. in medical sciences, professor, Department of Hospital Pediatrics</p><p>Saint-Petersburg</p></bio><xref ref-type="aff" rid="aff-9"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МИ СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>MI, M.K. Ammosov NEFU</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Респ. больница-НЦМ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>CRC at the Republican Hospital No.1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>Респ. больница-НЦМ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Republican Hospital No.1</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>Респ. больница-НЦМ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Republican Clinic No.1-NCM</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>Респ. больница-НЦМ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Republican Hospital № 1 of the National Center for Mental Health</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>МИ СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>TA MI M.K. Ammosov NEFU</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-7"><aff xml:lang="ru"><institution>МИ СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Institute of M.K. Ammosov North-East Federal University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-8"><aff xml:lang="ru"><institution>МИ СВФУ им. М.К. Аммосова; ЯНЦ КМП</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.K. Ammosov NEFU, chief researcher and head of the laboratory of the Yakut Scientific Centre for Complex Medical Problems</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-9"><aff xml:lang="ru"><institution>СПбГПМУ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saint-Petersburg State Pediatric Medical University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2022</year></pub-date><pub-date pub-type="epub"><day>04</day><month>02</month><year>2025</year></pub-date><volume>0</volume><issue>2</issue><fpage>126</fpage><lpage>128</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Иванова О.Н., Аргунова В.М., Слепцова П.А., Афонская М.В., Иннокентьева С.И., Иванова И.С., Аргунова Т.А., Бурцева Т.Е., Колобова О.Л., Чикова И.А., Сантимов А.В., Костик М.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Иванова О.Н., Аргунова В.М., Слепцова П.А., Афонская М.В., Иннокентьева С.И., Иванова И.С., Аргунова Т.А., Бурцева Т.Е., Колобова О.Л., Чикова И.А., Сантимов А.В., Костик М.М.</copyright-holder><copyright-holder xml:lang="en">Ivanova O.N., Argunova V.M., Sleptsova P.A., Afonskaya M.V., Innokentyeva S.I., Ivanova I.S., Argunova T.A., Burtseva T.E., Kolobova O.L., Chikova I.A., Santimov A.V., Kostik M.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/156">https://ymj.elpub.ru/jour/article/view/156</self-uri><abstract><p>АНЦА-ассоциированный васкулит (ААВ) - группа заболеваний, характеризующихся хроническим иммунным воспалением стенки мелких сосудов, полиморфной клинической картиной с частым вовлечением легких и почек и наличием циркулирующих аутоантител к цитоплазме нейтрофилов (АНЦА). В статье представлен клинический случай АНЦА-ассоциированного системного васкулита с поражением легких и почек.</p></abstract><trans-abstract xml:lang="en"><p>ANCA-associated vasculitis (AAV) is a group of diseases characterized by chronic immune inflammation of the wall of small vessels, a polymorphic clinical picture with frequent involvement of the lungs and kidneys, and the presence of circulating autoantibodies to the neutrophil cytoplasm (ANCA). The article presents a clinical case of ANCA-associated systemic vasculitis affecting the lungs and kidneys.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>АНЦА</kwd><kwd>васкулит</kwd><kwd>воспаление</kwd><kwd>легкие</kwd><kwd>почки</kwd><kwd>ребенок</kwd></kwd-group><kwd-group xml:lang="en"><kwd>ANCA</kwd><kwd>vasculitis</kwd><kwd>inflammation</kwd><kwd>lungs</kwd><kwd>kidneys</kwd><kwd>child</kwd></kwd-group><funding-group><funding-statement xml:lang="ru">Работа выполнена в рамках темы НИР ФГБНУ «ЯНЦ КМП» «Физическое развитие и состояние здоровья детского населения в условиях Крайнего Севера (на примере Якутии)» (номер госрегистрации: 1021062411641-9-3.2.3), в рамках госзадания Министерства науки и образования РФ (FSRG-2020-0016).</funding-statement></funding-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">АНЦА-ассоциированные васкулиты с доминирующим поражением почек: клинико-морфологическая презентация и исходы / В.А. 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