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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-1481</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ВОПРОСЫ ГЕОГРАФИЧЕСКОЙ ПАТОЛОГИИ И АДАПТАЦИИ: ЗЛОКАЧЕСТВЕННЫЕ НОВООБРАЗОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ISSUES OF GEOGRAPHICAL PATHOLOGY AND ADAPTATION: CANCERS</subject></subj-group></article-categories><title-group><article-title>Современный метод раннего выявления преонкологических изменений слизистой желудка</article-title><trans-title-group xml:lang="en"><trans-title>A modern method of early diagnosis of preoncologic changes of gastric mucosa</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сосина</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sosina</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сосина Светлана Степановна – к.м.н., доцент МИ.</p></bio><bio xml:lang="en"><p>Svetlana S. Sosina – cand. med. sciences, senior lecturer of the department of propaedeutic and faculty therapy with endocrinology and ART, Medical institute Northeast federal university of M.K. Ammosov.</p></bio><email xlink:type="simple">sosinasveta@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гольдерова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Golderova</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гольдерова Айталина Семеновна – д.м.н., зав., гл. н.с.</p></bio><bio xml:lang="en"><p>Ajtalina S. Golderova – doctor of med. sciences, head, chief researcher of FSBSI «YSC CMP».</p></bio><email xlink:type="simple">hoto68@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лоскутова</surname><given-names>К. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Loskutova</surname><given-names>K. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лоскутова Кюнняй Саввична – к.м.н., зав. патологоанатомич. отделом РБ№1 НЦМ, гл. внештат. патологоанатом МЗ РС(Я).</p></bio><bio xml:lang="en"><p>Kjunnjaj S. Loskutova – cand. med. sciences, chief non‐staff pathologist RS (Y); head of pathologic department RH 1‐NCM.</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефремова</surname><given-names>С. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Efremova</surname><given-names>S. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ефремова Светлана Дмитриевна – м.н.с.</p></bio><bio xml:lang="en"><p>Svetlana D. Efremova – junior research associate of FSBSI “YSC CMP”.</p></bio><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseeva</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексеева Елизавета Александровна – м.н.с.</p></bio><bio xml:lang="en"><p>Elizaveta A. Alekseeva ‐ junior research associate of FSBSI “YSC CMP”.</p></bio><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">СВФУ им. М.К. Аммосова<country>Россия</country></aff><aff xml:lang="en">Northeast federal university of M.K. Ammosov<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru">ФГБНУ «ЯНЦ КПМ»<country>Россия</country></aff><aff xml:lang="en">FSBSI «YSC CMP»<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru">РБ№1 НЦМ<country>Россия</country></aff><aff xml:lang="en">RH 1‐NCM<country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru">ФГБНУ «ЯНЦ КМП»<country>Россия</country></aff><aff xml:lang="en">FSBSI “YSC CMP”<country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>13</day><month>09</month><year>2025</year></pub-date><volume>0</volume><issue>2</issue><fpage>50</fpage><lpage>51</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Сосина С.С., Гольдерова А.С., Лоскутова К.С., Ефремова С.Д., Алексеева Е.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Сосина С.С., Гольдерова А.С., Лоскутова К.С., Ефремова С.Д., Алексеева Е.А.</copyright-holder><copyright-holder xml:lang="en">Sosina S.S., Golderova A.S., Loskutova K.S., Efremova S.D., Alekseeva E.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1481">https://ymj.elpub.ru/jour/article/view/1481</self-uri><abstract><p>С целью выявления преканцерогенных форм хронического гастрита в условиях Севера с использованием современных неинвазивных иммунноферментных методов диагностики (тест-набор «GastroPanel») обследованы больные хроническим гастритом - жители поселков Витим и Толон Ленского района РС(Я).</p><p>Выявлено, что метод обследования «Гастропанель» позволяет получить информацию о структуре и функции слизистой желудка, идентифицировать с высокой чувствительностью и специфичностью больных с выраженным атрофическим гастритом, относящихся к группе онкологического риска.</p></abstract><trans-abstract xml:lang="en"><p>In order to detect precancerous forms of chronic gastritis in the conditions of the North with use of modern noninvasive immunoenzymometric methods of diagnostics (the GastroPanel test set) a number of population from the settlements Vitim and Tolon of the Lensky region of RS(Ya) with chronic gastritis are examined. We revealed that the survey method «Gastropanel» allows to receive information on structure and function of gastric mucosa as well as to identify patients with expressed atrophic gastritis referring to a group of oncological risk with high sensitivity and specificity.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>атрофический гастрит</kwd><kwd>«Гастропанель»</kwd><kwd>идентификация</kwd></kwd-group><kwd-group xml:lang="en"><kwd>atrophic gastritis</kwd><kwd>“Gastropanel”</kwd><kwd>identification</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Значение сывороточных показателей пепсиногена 1, пепсиногена 2 и гастрина 17 в диагностике атрофического гастрита / Н.Н. Васильев, К.М. Николаева, Л.Г. 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