<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE article PUBLIC "-//NLM//DTD JATS (Z39.96) Journal Publishing DTD v1.3 20210610//EN" "JATS-journalpublishing1-3.dtd">
<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-1440</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МАТЕРИАЛЫ ОЧЕРЕДНОГО НОМЕРА «ЯКУТСКОГО МЕДИЦИНСКОГО ЖУРНАЛА»</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MATERIALS OF THE «YAKUT MEDICAL JOURNAL» NEXT ISSUE</subject></subj-group></article-categories><title-group><article-title>Иммунные механизмы формирования гестационных осложнений и патологии тимуса плода новорожденного ребенка</article-title><trans-title-group xml:lang="en"><trans-title>Immune mechanisms of gestational complications and the thymus pathology of fetus and newborn</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колесникова</surname><given-names>С. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolesnikova</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Колесникова Софья Михайловна –  к.м.н., доцент, зав. кафедрой, декан ФПКиП</p></bio><email xlink:type="simple">Sofhia_03@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Левкова</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Levkova</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Левкова Елена Анатольевна – д.м.н., проф. РАЕН, директор психологического центра ДВГУПС</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Институт повышения квалификации специалистов здравоохранения МЗ хабаровского края</institution><country>Russian Federation</country></aff><aff xml:lang="ru" id="aff-2"><institution>РАЕН; ВГУПС</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2014</year></pub-date><pub-date pub-type="epub"><day>14</day><month>09</month><year>2025</year></pub-date><volume>0</volume><issue>2</issue><fpage>87</fpage><lpage>90</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Колесникова С.М., Левкова Е.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Колесникова С.М., Левкова Е.А.</copyright-holder><copyright-holder xml:lang="en">Kolesnikova S.N., Levkova E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1440">https://ymj.elpub.ru/jour/article/view/1440</self-uri><abstract><p>В статье рассматриваются иммунные механизмы формирования и течения гестационных осложнений, патологии тимуса у новорожденного ребенка. доказаны иммуноопосредованные изменения в плаценте и тимусе.</p></abstract><trans-abstract xml:lang="en"><p>In the article immune mechanisms of formation and the course of gestational complications, pathologies of newborn’s thymus are considered. The immune mediated changes in placenta and thymus are proved.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>беременность</kwd><kwd>плацента</kwd><kwd>тимус</kwd><kwd>Т-клеточное звено</kwd><kwd>цитокины</kwd></kwd-group><kwd-group xml:lang="en"><kwd>pregnancy</kwd><kwd>placenta</kwd><kwd>thymus</kwd><kwd>T-cell link</kwd><kwd>cytokines</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Кузнецова Т.В. Эволюция акушерской патологии в России / Т.В. Кузнецова, Л.П. Суханова, В.А. Глушенкова // Здравоохранение Рос. Федерации. – 2010. – № 4. – С. 27–32.</mixed-citation><mixed-citation xml:lang="en">Kuznetsova T.V. Obstetric pathology evolution in Russia / T.V. Kuznetsova, L.P. Sukhanova, V.A. Glushenkova // Zdravoohranenie Rossijskoj Federacii. - 2010. - № 4. - P. 27-32.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Милованов А.П. Патология системы мать – плацента – плод: рук-во для врачей / А.П. Милованов. – М.: Медицина, 1999. – 448 с.</mixed-citation><mixed-citation xml:lang="en">Milovanov A.P. Pathology of the system mother - placenta - fetus: manual for doctors / A.P. Milovanov. - M.: Medicina, 1999. - 448 p.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Радзинский В.Е. безопасное акушерство / В.Е. Радзинский, И.Н. Костин // Акушерство и гинекология. – 2007. – № 5. – С. 12–16.</mixed-citation><mixed-citation xml:lang="en">Radzinsky V.E. Safe obstetrics / V.E. Radzinsky, I.N. Kostin // Akusherstvo i ginekologija. - 2007. - № 5. - p. 12-16.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Радзинский В.Е. Преждевременные роды / В.Е. Радзинский, И.Н. Костин // Там же. – 2009. – № 4. – С. 16–19. Radzinsky V.E. Prematurity / V.E. Radzinsky, I.N. Kostin // Akusherstvo i ginekologija. - 2009. - № 4. - p. 16-19.</mixed-citation><mixed-citation xml:lang="en">Radzinsky V.E. Prematurity / V.E. Radzinsky, I.N. Kostin // Akusherstvo i ginekologija. - 2009. - № 4. - p. 16-19.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Сапин М.Р. Анатомия и физиология чело века с возрастными особенностями детского организма: учеб. / М.Р. Сапин, В.И. Сивогла зов. – 9-е изд. – М.: Академия, 2012. – 384 с.</mixed-citation><mixed-citation xml:lang="en">Sapin M.R. Human anatomy and physiology with child’s organism age features: textbook / M.R. Sapin, V.I. Sivoglazov. - 9th ed. – M.: Academia, 2012. – 384 p.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Тетруашвили Н.К. диагностическая и прогностическая значимость определения цитокинов у больных с привычным невынашиванием беременности: автореф. дис. … канд. мед. наук: 14.00.01 / Н.К. Тетруашвили. – М., 2000. – 22 с.</mixed-citation><mixed-citation xml:lang="en">Tetruashvili N.K. Diagnostic and prognostic value of determination of cytokines in patients with recurrent miscarriage: PhD dis. ... thesis: 14.00.01 / Tetruashvili N. K. - M., 2000. – 22 p.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Фрейдлин И.С. Иммунный гомеостаз: возрастные аспекты / И.С. Фрейдлин // Саногенез: моногр. / под ред. А.Н. Кокосова. – СПб., 2009. – С. 122–138.</mixed-citation><mixed-citation xml:lang="en">Freidlin I.S. Immune homeostasis: age aspects / I. S. Freidlin // SAnogenesis/ Ed. A.N. Kokosov. - SPb. - 2009. - Ch. 3.6. - p. 122-138.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Фрейдлин И.С. Структура, функции и регуляция иммунной системы / И.С. Фрейдлин // Иммунодефицитные состояния: моногр. / под ред. В.С. Смирнова, И.С. Фрейдлин. – СПб., 2000. – С. 17–90.</mixed-citation><mixed-citation xml:lang="en">Freidlin I. S. Structure, function and regulation of the immune system / I.S. Freidlin // Immune deficiency states: monograph / Ed. V.S. Smirnov, I.S. Freidlin. - SPb. - 2000. - p. 17-90.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Юсупова А.Н. Клинико-статистический анализ современных тенденций материнской смертности в России / А.Н. Юсупова, Л.П. Суханова, В.А. Глушенкова // Здравоохранение Рос. Федерации. – 2009. – № 4. – С. 14–19.</mixed-citation><mixed-citation xml:lang="en">Yusupova A.N. Clinical and statistical analysis of current trends in maternal mortality in Russia / A.N. Yusupova, L.P. Sukhanova, V.A. Glushenkova / Zdravoohranenie Rossijskoj Federacii. - 2009. - № 4. - p. 14-19.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Ярилин А.А. Основы иммунологии: учеб. / А.А. Ярилин. – М.: Медицина, 1999. – 608 с.</mixed-citation><mixed-citation xml:lang="en">Yarilin A.A. Fundamentals of Immunology: Textbook / A.A. Yarilin. - M.: Medicina, 1999. - 608 p.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Земскова А.М. Энциклопедия иммунологии. В 5 т. / Под ред. А.М. Земскова, В.М. Земскова, В.А. Черешнева. – Изд-во «Триада», 2013. – Т. 3. – С.165-192</mixed-citation><mixed-citation xml:lang="en">Zemskova A.M. Encyclopedia of immunology /ed. A.M. Zemskova, V.M. Zemskov, V.A. Chereshnev.- Izd-vo «Triada», 2013.- V. 3.- p.165-192.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Duckitt K. Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies / K. Duckitt, D. Harrington. – BMJ. – 2005. – Vol. 330, № 7491. – P. 565.</mixed-citation><mixed-citation xml:lang="en">Duckitt K. Risk factors for pre-eclampsia at antenatal booking: systematic review of controlled studies / K. Duckitt, D. Harrington. – BMJ. – 2005. – Vol. 330, № 7491. – P. 565.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Identifying risk factors for peripartum cesarean hysteroctomy. A population-based study / E. Sheiner, A. Levy, M. Katz, M. Mazor // J. Reprod. Med. – 2003. – Vol. 48, № 8. – P. 622–626.</mixed-citation><mixed-citation xml:lang="en">Identifying risk factors for peripartum cesarean hysteroctomy. A population-based study / E. Sheiner, A. Levy, M. Katz, M. Mazor // J. Reprod. Med. – 2003. – Vol. 48, № 8. – P. 622–626.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Peripartum hysterectomy in the 1990s: any new lessons? / F. Langdana, M. Geary, W. Haw, D. Keane // J. Obstet. Gynaecol. – 2001. – Vol. 21, № 2. – P. 121–123.</mixed-citation><mixed-citation xml:lang="en">Peripartum hysterectomy in the 1990s: any new lessons? / F. Langdana, M. Geary, W. Haw, D. Keane // J. Obstet. Gynaecol. – 2001. – Vol. 21, № 2. – P. 121–123.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Roopnarinesingh R. A 27-year review of obstetric hysterectomy / R. Roopnarinesingh, L. Fay, P. McKenna // J. Obstet. Gynaecol. – 2003. – Vol. 23, № 3. – P. 252–254.</mixed-citation><mixed-citation xml:lang="en">Roopnarinesingh R. A 27-year review of obstetric hysterectomy / R. Roopnarinesingh, L. Fay, P. McKenna // J. Obstet. Gynaecol. – 2003. – Vol. 23, № 3. – P. 252–254.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
