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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-1424</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>АКТУАЛЬНАЯ ТЕМА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ACTUAL TOPIC</subject></subj-group></article-categories><title-group><article-title>Хронические панкреатиты у детей Республики Саха (Якутия)</article-title><trans-title-group xml:lang="en"><trans-title>Chronic Pancreatitis at Children of the Republic of Sakha (Yakutia)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванова Ольга Николаевна – д.м.н., проф. МИ СВФУ </p></bio><bio xml:lang="en"><p>Ivanova Olga Nikolaevna, professor of the Department of Pediatrics and children's surgery, Medical institute</p><p>Yakutsk</p></bio><email xlink:type="simple">olgadoctor@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Березкина</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Berezkina</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>  – аспирант МИ СВФУ</p></bio><bio xml:lang="en"><p>Berezkina Olga Nikolaevna, postgraduate Department of Pediatrics and pediatric surgery of MI</p><p>Yakutsk</p></bio><email xlink:type="simple">berezkinaolga@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North‐East Federal University</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>13</day><month>09</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>80</fpage><lpage>81</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Иванова О.Н., Березкина О.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Иванова О.Н., Березкина О.Н.</copyright-holder><copyright-holder xml:lang="en">Ivanova O.N., Berezkina O.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1424">https://ymj.elpub.ru/jour/article/view/1424</self-uri><abstract><p>Статья посвящена актуальной проблеме изучения иммунного статуса у детей с патологией поджелудочной железы. При анализе изменений иммунного статуса у детей с хроническими панкреатитами выявлены наибольшее снижение показателей Т-клеточного звена и компонентов комплемента, снижение содержания иммуноглобулина А, IFN-γ, FNO-ά.</p></abstract><trans-abstract xml:lang="en"><p>This article is devoted to the study of the immune status in children with pathology of the pancreas. At the analysis of changes of immune status in children with chronic pancreatitis we revealed the greatest decline in T-cell level and components of complement, a decrease level of immunoglobulin A, IFN-γ, FNO-ά.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>иммунитет</kwd><kwd>панкреатит</kwd><kwd>субпопуляции лимфоцитов</kwd><kwd>интерфероны</kwd><kwd>фактор некроза опухоли</kwd><kwd>цитокины</kwd><kwd>интерлейкины</kwd></kwd-group><kwd-group xml:lang="en"><kwd>immune system</kwd><kwd>pancreatitis</kwd><kwd>lymphocyte subpopulations</kwd><kwd>interferons</kwd><kwd>tumor necrosis factor</kwd><kwd>cytokines</kwd><kwd>interleukins</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Данилов М.В. Хирургия поджелудочной железы: руководство для врачей / М.В. Данилов, В.Д. Федоров. – М., 1995.</mixed-citation><mixed-citation xml:lang="en">Danilov M. V. Fedorov V. D. 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Хазанова. – М., 2000.</mixed-citation><mixed-citation xml:lang="en">Statisticheskij godovoj otchet za 2002 g. po gastrojenterologicheskomu otdeleniju PC RB № 1‐NCM [Statistical annual report for 2002 of the Gastroenterology Department in the PCRH № 1‐NCM].</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
