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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-1377</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕТОДЫ ДИАГНОСТИКИ И ЛЕЧЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>METHODS OF DIAGNOSIS AND TREATMENT</subject></subj-group></article-categories><title-group><article-title>Характеристика антимикробной активности препарата «Ягель» при воспалительном процессе краевой десны</article-title><trans-title-group xml:lang="en"><trans-title>Characteristics of the “Yagel” Preparation Antimicrobial Activity at the Edge Gingival Inflammation Authors</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Черемкина</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Cheremkina</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Черемкина Анна Сергеевна – ст. преподаватель, Медицинский институт </p></bio><bio xml:lang="en"><p>Cheremkina Anna Sergeevna, Senior lecturer of department of therapeutic, surgical, orthopedic dentistry and dentistry of children's age of Medical Institute</p><p>677016, Oiunsky Str 27, Yakuts</p></bio><email xlink:type="simple">cheremkina@bk.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ушницкий</surname><given-names>И. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Ushnitsky</surname><given-names>I. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ушницкий Иннокентий Дмитриевич – зав. кафедрой, Медицинский институт </p></bio><bio xml:lang="en"><p>Ushnitsky Innokenty Dmitrievitch, PhD, Head of the department of therapeutic, surgical, orthopedic dentistry and dentistry of children's age of Medical Institute </p><p>677016, Oiunsky Str 27, Yakutsk</p></bio><email xlink:type="simple">incadim@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ахременко</surname><given-names>Я. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Akhremenko</surname><given-names>Ya. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ахременко Яна Александровна – к.м.н., доцент, зав. курсом, с.н.с. Учебно-научной микробиологической лаборатории Клиники МИ СВФУ</p></bio><bio xml:lang="en"><p>Akhremenko Yana Aleksandrovna, Candidate of medical sciences, Senior lecturer of department of histology and microbiology. A course of microbiology and immunology of Medical Institute; Senior research officer of scientific microbiologic laboratory of Clinic Medical Institute</p><p>677016, Oiunsky Str 27, Yakutsk</p><p> </p></bio><email xlink:type="simple">yanalex2007@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Никифорова</surname><given-names>Е. Ю.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikiforova</surname><given-names>E. Y.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Никифорова Екатерина Юрьевна – ассистент кафедры, Медицинский институт </p></bio><bio xml:lang="en"><p>Nikiforova Ekaterina Yurevna, Assistant of department of therapeutic, surgical, orthopedic dentistry and dentistry of children's age of Medical Institute </p><p>677016, Oiunsky Str 27, Yakutsk</p></bio><email xlink:type="simple">Feay88@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тарасова</surname><given-names>Л. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Tarasova</surname><given-names>L. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тарасова Лидия Андреевна – к.м.н., доцент, с.н.с. Учебно-научной микробиологической лаборатории Клиники МИ СВФУ</p></bio><bio xml:lang="en"><p>Tarasova Lydia Andreevna, Candidate of medical sciences, Assistant professor of department of histology and microbiology of Medical Institute of the North‐Eastern federal university named after M.K.Ammosov, Senior research officer of scientific microbiologic laboratory of Clinic Medical Institute </p><p>677016, Oiunsky Str 27, Yakutsk</p></bio><email xlink:type="simple">degtyarevalida@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Прокопьев</surname><given-names>И. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Prokopiev</surname><given-names>I. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p> Прокопьев Илья Андреевич – к.б.н., н.с. </p></bio><bio xml:lang="en"><p>Prokopiev Ilya Andreevitch, Research assistant, Candidate of biological sciences, laboratory of ecological and medical biological chemistry</p><p>41, Lenin avenue, Yakutsk, 677000 </p></bio><email xlink:type="simple">Ilya.a.prokopiev@gmail.com</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North‐Eastern federal university named after M.K.Ammosov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ИБПК СО РАН</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Siberian Branch of the Russian Academy of Science</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>13</day><month>09</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>33</fpage><lpage>35</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Черемкина А.С., Ушницкий И.Д., Ахременко Я.А., Никифорова Е.Ю., Тарасова Л.А., Прокопьев И.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Черемкина А.С., Ушницкий И.Д., Ахременко Я.А., Никифорова Е.Ю., Тарасова Л.А., Прокопьев И.А.</copyright-holder><copyright-holder xml:lang="en">Cheremkina A.S., Ushnitsky I.D., Akhremenko Y.A., Nikiforova E.Y., Tarasova L.A., Prokopiev I.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1377">https://ymj.elpub.ru/jour/article/view/1377</self-uri><abstract><p>Изучены распространенность и интенсивность заболеваний пародонта у детей школьного возраста, а также подростков г. Якутска. У обследованных детей определялся высокий уровень частоты гингивита, наиболее часто выявлялась его катаральная форма и реже локализованный хронический пародонтит легкой степени. Проведено изучение антимикробной активности биопрепарата «Ягель» к условно-патогенной микрофлоре при гингивите. Показано, что использование «Ягель» оказывает влияние на количественные и качественные показатели грамположительных, грамотрицательных микроорганизмов, а также грибов рода Candida, которые способствуют развитию воспалительного процесса краевой десны. В связи с этим данное средство может применяться в комплексной терапии гингивита в качестве альтернативного средства.</p></abstract><trans-abstract xml:lang="en"><p>The prevalence and intensity of parodontium diseases among children of school age and also teenagers of educational institutions of Yakutsk have been studied. Their high level of frequency in these examined groups where mostly chronic catarrhal gingivitis and rarer localised chronic periodontitis of mild case were defined. On the other hand, the unsatisfactory oral cavity hygiene was revealed in these groups of children that accordingly characterized insufficient level of sanitary culture of children and their parents. We’ve chosen preparation "Yagel" for the research. It is made of native vegetative raw materials of frond lichens extract of Cladina family. It has a high maintenance of usnicand other lichen derivative acids in clathrate shape with lichen β ‐ oligosaccharides and possesses the antimicrobial action which hasn’t been studied earlier in clinical dentistry. Taking it into account we’vestudied antibiotic action of "Yagel" to conditional‐ pathogenic microflora incase of gingivitis. The microbiologicassessment of this medication has revealed certain features of minimum inhibiting concentration and minimum bactericidal concentration. So, the use of "Yagel" affected on quantitative and quality indicators of gram‐ positive, gram‐negative microorganisms and also Candidainfection. The revealed inhibiting and bactericidal concentration of "Yagel" allowed to assert that it could promote reverse development of inflammatory process of gum tissues in the clinical plan and accordingly, reduce period of treatment and help treatment‐and‐prophylactic efficacy. In this connection this preparation could be applied in complex gingivitis therapy as alternative medication. Thus "Yagel" is produced in Yakutsk that defines its low cost price and availability for a wide range of the population. There is a necessity of further researches of clinical efficacy of "Yagel" in pathological processes of parodontium tissues of inflammatory‐destructive character.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>гингивит</kwd><kwd>пародонтит</kwd><kwd>стоматологическая помощь</kwd><kwd>экстракт лишайника</kwd><kwd>микроорганизмы</kwd><kwd>питательная среда</kwd><kwd>антимикробное действие</kwd></kwd-group><kwd-group xml:lang="en"><kwd>gingivitis</kwd><kwd>periodontitis</kwd><kwd>dental care</kwd><kwd>lichen extract</kwd><kwd>microorganisms</kwd><kwd>nutrient medium</kwd><kwd>antimicrobial action</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Бакшеева С.Л. Научное обоснование концепции оптимизации стоматологической помощи взрослому населению Эвенкии: дис… д-ра мед. наук : код спец. 14.01.14 / С.Л. Бакшеева; ГБОУ ВПО «Красн. гос. мед. ун-т им. проф. В.Ф. 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