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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">ymj-1299</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Влияние хронических заболеваний гепатодуоденопанкреатической зоны на результаты лапароскопической холецистэктомии</article-title><trans-title-group xml:lang="en"><trans-title>Infuence of Chronic Diseases of a Gepatoduodenopancreatic Zone on Results of Laparoscopic Cholecystectomy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Петров</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Petrov</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Петров Валерий Сергеевич – к.м.н., ген. директор</p></bio><bio xml:lang="en"><p>Valeriy Sergeyevich Petrov – Candidate of Medicine, director general  </p><p>677019, 4 Sergelyakhskoye Chaussee, Yakutsk Phone: 8 (4112)395000 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тобохов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tobokhov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Тобохов Александр Васильевич – д.м.н., проф., зав. кафедрой</p></bio><bio xml:lang="en"><p>Alexander Vasilyevich Tobokhov – Professor, Doctor of Medical Science, head of the hospital surgery and radiology chair at the Medical Institute</p><p>677010, 4 Sergelyakhskoye Chaussee, Yakutsk Phone: 8 (4112)395644 </p></bio><email xlink:type="simple">avtobohov@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаев</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaev</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Николаев Владимир Николаевич – к.м.н., доцент</p></bio><bio xml:lang="en"><p>Vladimir Nikolayevich Nikolayev - Candidate of Medicine, associate professor of the hospital surgery and radiology chair at the Medical Institute</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ГБУ Республики Саха (Якутия) «РБ №1 – Национальный центр медицины»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Republic of Sakha (Yakutia) state entity Republic’s Hospital N1 – National Center of Medicine</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГАОУ ВПО «Северо-Восточный федеральный университет им. М.К. Аммосова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>North-East Federal University named after M.K. Ammosov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2015</year></pub-date><pub-date pub-type="epub"><day>12</day><month>09</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>12</fpage><lpage>14</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Петров В.С., Тобохов А.В., Николаев В.Н., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Петров В.С., Тобохов А.В., Николаев В.Н.</copyright-holder><copyright-holder xml:lang="en">Petrov V.S., Tobokhov A.V., Nikolaev V.N.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1299">https://ymj.elpub.ru/jour/article/view/1299</self-uri><abstract><p>Проанализированы результаты 2778 случаев хирургического лечения желчнокаменной болезни. Установлено, что сочетание желчнокаменной болезни (ЖКБ) с заболеваниями органов гепатодуоденопанкреатической зоны достоверно увеличивает риск выполнения лапароскопической холецистэктомии (ЛХЭ). Основным фактором риска является большая частота спаечных процессов, что требует разработки модифицированной хирургической тактики. При определении хирургической тактики лечения ЖКБ в сочетании с вирусными гепатитами целесообразно ориентироваться на иммуноферментные маркеры активности гепатита. При иммунологически неактивных формах вирусного гепатита хирургическое лечение ЖКБ является оправданным, так как восстанавливает адекватный отток желчи и ликвидирует воспалительный очаг. Применение ЛХЭ у больных с сахарным диабетом является оправданным, так как дает возможность предотвратить развитие деструктивных форм холецистита.</p></abstract><trans-abstract xml:lang="en"><p>The results of 2778 cases of surgical treatment of cholelithiasis are analyzed in this article. The authors detected that the combination of chronic cholelithiasis with diseases of the hepatoduodenopancreatic zone significantly increases risk of performing the laparoscopic cholecystectomy (LCE). High frequency of adhesion is considered as a prime factor, requiring the development of a modified surgical approach. When determining the surgical approach of cholelithiasis treatment in the combination with virus hepatitis it is viable to be guided by immunoenzymometric markers of hepatitis activity. In immunologic inactive forms of virus hepatitis the surgical treatment of cholelithiasis is justified as it restores an appropriate bile outflow and eliminates the inflammatory process. Applying the laparoscopic cholecystectomy at patients with diabetes was justified as well, it preventing obviously the development of destructive forms of cholecystitis.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лапароскопическая холецистэктомия</kwd><kwd>желчнокаменная болезнь</kwd><kwd>осложнения операций</kwd></kwd-group><kwd-group xml:lang="en"><kwd>laparoscopic cholecystectomy</kwd><kwd>cholelithiasis</kwd><kwd>complications of surgery</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Гальперин Э.И. аболевания желчных путей после хлецистэктомии / Э.И. Гальперин, Н.В. Волкова. – М.: Медицина, 1988. – 272 с.</mixed-citation><mixed-citation xml:lang="en">Galperin E.I. Diseases of biliary tracts after cholecystectomy / E.I. Galperin, N.V. Volkova. – M.: Meditsina, 1988. – 272 p.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Hamy A. Endoscopic sphincterotomy prior to laparoscopic cholecystectomy for the treatment of cholelithiasis / Hamy A., Hennekinne S., Pessaux P. // Surg Endosc. – 2003. – V.17. – N.6. - P.872-875.</mixed-citation><mixed-citation xml:lang="en">Hamy A. Endoscopic sphincterotomy prior to laparoscopic cholecystectomy for the treatment of cholelithiasis / Hamy A., Hennekinne S., Pessaux P. // Surg Endosc. – 2003. – V.17. – N.6. - P.872-875.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
