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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2018.62.12</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-1259</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МАТЕРИАЛЫ НАУЧНО-ПРАКТИЧЕСКОЙ КОНФЕРЕНЦИИ С МЕЖДУНАРОДНЫМ УЧАСТИЕМ «ВЛИЯНИЕ ХОЛОДА НА ОРГАНИЗМ ЧЕЛОВЕКА»</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>MATERIALS OF SCIENTIFIC-PRACTICAL CONFERENCE WITH INTERNATIONAL PARTICIPATION «THE INFLUENCE OF COLD ON THE HUMAN ORGANISM»</subject></subj-group></article-categories><title-group><article-title>Состояние антиоксидантной защиты организма у больных ишемической болезнью сердца в условиях Севера в зависимости от этнической принадлежности</article-title><trans-title-group xml:lang="en"><trans-title>The state of antioxidant protection of the body in patients with coronary heart disease in the North depending on ethnicity</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлева</surname><given-names>А. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovleva</surname><given-names>A. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ЯКОВЛЕВА Александра Ивановна – н.с.</p></bio><bio xml:lang="en"><p>Yakovleva Alexandra Ivanovna – researcher</p><p>Yakutsk</p></bio><email xlink:type="simple">sashyak@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Охлопкова</surname><given-names>Е. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Okhlopkova</surname><given-names>E. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ОХЛОПКОВА Елена Дмитриевна – к.б.н., вед.н.с.-руковод. лаб.</p></bio><bio xml:lang="en"><p>Okhlopkova Elena Dmitrievna – c.b.s., leading specialist</p><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кривошапкина</surname><given-names>З. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Krivoshapkina</surname><given-names>Z. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>КРИВОШАПКИНА Зоя Николаевна – к.б.н., с.н.с.</p></bio><bio xml:lang="en"><p>Krivoshapkina Zoya Nikolaevna - c.b.s., senior researcher</p><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефремова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Efremova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ЕФРЕМОВА Аграфена Владимировна – к.б.н., с.н.с.</p></bio><bio xml:lang="en"><p>Efremova Agrafena Vladimirovna - c.b.s., senior researcher </p><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Константинова</surname><given-names>Л. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Konstantinova</surname><given-names>L. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>КОНСТАНТИНОВА Лена Ивановна – н.с.</p></bio><bio xml:lang="en"><p>KONSTANTINOVA Lena Ivanovna</p><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Миронова</surname><given-names>Г. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Mironova</surname><given-names>G. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>МИРОНОВА Галина Егоровна – д.б.н., проф.</p></bio><bio xml:lang="en"><p>Mironova Galina Egorovna – d.b.s., prof., biological branch</p><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Олесова</surname><given-names>Л. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Olesova</surname><given-names>L. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ОЛЕСОВА Любовь Дыгыновна – к.б.н., вед.н.с.-руковод. лаб.</p></bio><bio xml:lang="en"><p>Olesova Lyubov Dygynovna - c.b.s., leading researcher</p><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Семенова</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Semenova</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>СЕМЕНОВА Евгения Ивановна – к.б.н., с.н.с.</p></bio><bio xml:lang="en"><p>Semenova Eugenia Ivanovna - c.b.s., senior researcher </p><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБНУ ЯНЦ КМП</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSBSU “Yakutsk Scientific Center of Complex Medical Problems”</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ФГБНУ ЯНЦ КМП; ИЕН СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>FSBSU “Yakutsk Scientific Center of Complex Medical Problems”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>09</day><month>09</month><year>2025</year></pub-date><volume>0</volume><issue>2</issue><fpage>38</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Яковлева А.И., Охлопкова Е.Д., Кривошапкина З.Н., Ефремова А.В., Константинова Л.И., Миронова Г.Е., Олесова Л.Д., Семенова Е.И., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Яковлева А.И., Охлопкова Е.Д., Кривошапкина З.Н., Ефремова А.В., Константинова Л.И., Миронова Г.Е., Олесова Л.Д., Семенова Е.И.</copyright-holder><copyright-holder xml:lang="en">Yakovleva A.I., Okhlopkova E.D., Krivoshapkina Z.N., Efremova A.V., Konstantinova L.I., Mironova G.E., Olesova L.D., Semenova E.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1259">https://ymj.elpub.ru/jour/article/view/1259</self-uri><abstract><p>Целью настоящей работы явилось исследование состояния антиоксидантной защиты организма у больных ишемической болезнью сердца, проживающих на Севере, в зависимости от этнической принадлежности.</p><p>Было выявлено, что у больных ИБС из коренного и пришлого населения дислипидемия характеризуется повышением в крови уровня триглицеридов. дизадаптация к северным условиям происходит за счет активации процессов липопероксидации, которая обусловлена накоплением малонового диальдегида и сопровождается угнетением антиоксидантного потенциала организма.</p></abstract><trans-abstract xml:lang="en"><p>The state of antioxidant protection of the body in patients with coronary heart disease, depending on ethnicity in the North, was under study.</p><p>It was revealed that dyslipidemia in patients with coronary heart disease is characterized by an increase in the level of triglycerides in blood. Dysadaptation to the northern conditions occurs due to the activation of lipid peroxidation processes, which is caused by the accumulation of malonicdialdehyde and is accompanied by inhibition of the antioxidant potential of the organism.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>ишемическая болезнь сердца</kwd><kwd>перекисное окисление липидов</kwd><kwd>антиоксидантная защита организма</kwd><kwd>Север</kwd></kwd-group><kwd-group xml:lang="en"><kwd>coronary heart disease</kwd><kwd>lipid peroxidation</kwd><kwd>antioxidant protection of the organism</kwd><kwd>North</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Алексеева Т.И. Адаптационные процессы в популяциях человека / Т.И. Алексеева. М.: Изд-во Моск. ун-та, 1986. – 218 с.</mixed-citation><mixed-citation xml:lang="en">Alekseyeva T.I. Adaptatsionnyye protsessy v populyatsiyakh cheloveka [Adaptation processes in human populations]. Moscow: izd-vo Mosk. un-ta [publ. of the Mosc. Univ.], 1986.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Ланкин В.З. Перекиси липидов и атеросклероз / В.З. Ланкин, А.К. Тихазе, Н.В. Кошелевцева // Кардиология. – 1987. – №2. – С.23-30.</mixed-citation><mixed-citation xml:lang="en">Lankin V.Z., Tikhaze A.K., Koshelevtseva N.V. Perekisi lipidov i ateroskleroz [Lipid peroxidation and atherosclerosis] Kardiologiya [Cardiology]. 1987, No. 2, p. 23-30.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Меерсон Ф.З. Адаптация, стресс и профилактика / Ф.З. Меерсон. М.: Наука, 1981. –280 с.</mixed-citation><mixed-citation xml:lang="en">Meyerson F.Z. Adaptatsiya, stress i profilaktika [Adaptation, stress and prevention]. Moscow: Nauka [Science], 1981.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Мостахов И.М. Климато-географическая характеристика Якутии / И.М. Мостахов. – Якутск, 1983. – 245 с.</mixed-citation><mixed-citation xml:lang="en">Mostakhov I.M. Klimato-geograficheskaya kharakteristika Yakutii [Climato-geographic characteristics of Yakutia]. Yakutsk, 1983.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Оганов Р.Г. Профилактика сердечно-сосудистых заболеваний – реальный путь улучшения демографической ситуации в России / Р.Г Оганов., Г.Я. Масленникова // Кардиология. – 2007. – № 47 (1). – С. 4-7.</mixed-citation><mixed-citation xml:lang="en">Oganov R.G., Maslennikova G.YA. Profilaktika serdechno-sosudistykh zabolevaniy – real’nyy put’ uluchsheniya demograficheskoy situatsii v Rossii [Prevention of cardiovascular diseases - a real way to improve the demographic situation in Russia] Kardiologiya [Cardiology]. 2007, No. 47 (1), p. 4-7.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Орехов К.В. Экстремальные факторы Крайнего Севера и вопросы здоровья населения этого района / К.В. Орехов // Вестник АМН СССР. – 1979. – № 6. – С. 73-82.</mixed-citation><mixed-citation xml:lang="en">Orekhov K.V. Ekstremal’nyye factory Kraynego Severa I voprosy zdorov’ya naseleniya etogorayona [Extreme factors of the Far North and public health issues in the area / K.V. Orekhov] Vestnik AMN SSSR [Bulletin of the AMS of the USSR].1979, No. 6, p. 73-82.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Панин Л.Е. Полярный метаболический тип / Л.Е. Панин // Вопросы экологии человека в условиях Крайнего Севера. – Новосибирск, 1979. – С. 23-32.</mixed-citation><mixed-citation xml:lang="en">Panin L.Ye. Polyarnyy metabolicheskiy tip [Polar metabolic type] V kn.: Voprosy ekologii cheloveka v usloviyakh Kraynego Severa North [In: Problems of human ecology in the Far] Otvetstv. red. Panin L.Ye. [Responsibilities ed. L.E. Panin]. Novosibirsk: 1979, p. 23-32.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Патология человека на Севере / П.П. Авцын, А.А. Жаворонков, А.Г, Марачев, А.П. Милованов. – МАН СССР. – М.: Медицина, 1985. – 415 с.</mixed-citation><mixed-citation xml:lang="en">Avtsyn P.P., A.A. Zhavoronkov, A.G Marachev, A.P. Avtsyn, A.P. Milovanov. Patologiya cheloveka na Severe [The pathology of man in the North]. MAN SSSR. Moscow: Medicina, 1985.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Роль дислипидемии в патогенезе сосудистых катастроф среди населения Заполярья / Л.Н. Маслов, Е.А. Вычужанова, А.С. Горбунов, С.Ю. Цибульников // Вестник РАМН. – 2014. – № 7-8. – С. 133-136.</mixed-citation><mixed-citation xml:lang="en">Maslov L.N., Vychuzhanova Ye.A., Gorbunov A.S., Tsibul’nikov S.Yu. Rol’ dislipidemii v patogeneze sosudistykh katastrof sredi naseleniya Zapolyar’ya [The role of dyslipidemia in the pathogenesis of vascular accidents among the population of the Arctic Circle] Vestnik RAMN [Bulletin of the RAMS]. 2014, No. 7-8, p. 133-136.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Рослый И.М. Ферментемия – адаптивный механизм или маркер цитолиза / И.М. Рослый, С.В. Абрамов, В.И. Покровский // Вестник РАМН. – 2002. – № 8. – С. 3-8.</mixed-citation><mixed-citation xml:lang="en">Roslyy I.M., Abramov S.V., Pokrovskiy V.I. Fermentemiya – adaptivnyy mekhanizm ili marker tsitoliza [Enzyme is an adaptive mechanism or marker of cytolysis] Vestnik RAMN [Bulletin of the RAMS]. 2002, No. 8, p. 3-8.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Тихонов Д.Г. некоторые проблемы патогенеза и клинических проявлений атеросклероза (ишемической болезни сердца, гипертонической болезни) на Крайнем Севере / Д.Г. Тихонов, В.П. Николаев, В.И. Седалищев // Тер. архив. 2011. – № 83 (1). – С. 63-69.</mixed-citation><mixed-citation xml:lang="en">Tikhonov D.G., Nikolayev V.P., Sedalishchev V.I. Nekotoryye problemy patogeneza i klinicheskikh proyavleniy ateroskleroza (ishemicheskoy bolezni serdtsa, gipertonicheskoy bolezni) na Kraynem Severe [Some problems of pathogenesis and clinical manifestations of atherosclerosis (coronary heart disease, hypertensive disease) in the Far North] Ter. arkhiv. [Ther. arch.]. 2011, No 83 (1), p. 63-69.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Экология человека: Словарь справочник / авт.-сост. Н.А. Агаджанян, И.Б. Ушаков, В.И. Торшин и др. / под общ. ред. Н.А. Агаджаняна. – М.: Экоцентр, 1997. –208 с.</mixed-citation><mixed-citation xml:lang="en">Ekologiya cheloveka: Slovar’ spravochnik [Human ecology: Dictionary reference book] Avt.-sost. N.A. Agadzhanyan, I.B. Ushakov, V.I. Torshin i dr.; pod obshch. red. N.A. Agadzhanyana [edited by N.A. Agadzhanyan]. Moscow: Kruk [Crook], 1997.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Эпидемиология ишемической болезни сердца и особенности атеросклероза у мужчин Якутска / В.П. Алексеев, К.И. Иванов, В.В. Константинов и др. // Тер. архив. – 2001. – №73 (1). – С.12-18.</mixed-citation><mixed-citation xml:lang="en">Alekseyev V.P., Ivanov K.I., Konstantinov V.V. i dr. Epidemiologiya ishemicheskoy bolezni serdtsa i osobennosti ateroskleroza u muzhchin Yakutska [Epidemiology of coronary heart disease and features of atherosclerosis in Yakutsk men]. Ter. ark. [Ter. arch.]. 2001, No. 73 (1), p. 12-18.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Melnikov V.N. Life span of people who died from cardiovascular diseases in Siberia: a comporative study of two populations / V.N. Melnikov // Int. J. Circumpolar. Health.-2003. №62 (3). – р. 296-307.</mixed-citation><mixed-citation xml:lang="en">Melnikov V.N. Life span of people who died from cardiovascular diseases in Siberia: a comparative study of two populations / V.N. Melnikov Int. J. Circumpolar. Health. 2003. - 62 (3). – Р. 296-307.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
