ymjЯкутский медицинский журналYakut Medical Journal1813-19052312-1017ЯНЦ КМП10.25789/YMJ.2018.64.30ymj-1193Research ArticleНАУЧНЫЕ ОБЗОРЫ И ЛЕКЦИИSCIENTIFIC REVIEWS AND LECTURESДиагностическое значение определения вируса папилломы человека в кровиDiagnostic significance of the human papilloma virus detection in bloodКононоваИ. В.KononovaI. V.

Кононова Ирина Васильевна – к.м.н., н.с. 

Kononova Irina Vasilyevna – Candidate of Medical Sciences, the Research Worker of YSC CMP Department of epidemiology of chronic non-communicable diseases Laboratory of Precancerogenesis and Malignant Tumors

677000, Yakutsk, Sergelyakhskoye shosse, 4 

irinakon.07@mail.ruЗахароваФ. А.ZakharovaF. A.

Захарова Федора Апполоновна – д.м.н., проф. 

Zakharova Fedora Apollonovna – Doctor of Medical Sciences, Professor of North-Eastern Federal University named after M. K. Ammosov Medical Institute Department of Normal and Pathological Physiology

677000, Yakutsk, ulitsa Belinskogo, 58  

kirillinamp@mail.ruКириллинаМ. П.KirillinaM. P.

Кириллина Мария Петровна – к.б.н., в.н.с.-руковод. лаб., зав. лаб. МИ СВФУ им. М.К. Аммосова 

Kirillina Marya Petrovna – Candidate of Biological Sciences, the Leading Research Worker – the Head of YSC CMP Department of epidemiology of chronic non-communicable diseases Laboratory of Precancerogenesis and Malignant Tumors; the Head of North Eastern Federal University named after M. K. Ammosov Medical Institute Pathomorphology, Histology and Cytology Educational and Scientific Laboratory

677000, Yakutsk, Sergelyakhskoye shosse, 4 

Yakutsk, ulitsa Belinskogo, 58 

НикифоровП. В.NikiforovP. V.

Никифоров Петр Владимирович – врач онколог, хирург  

Nikiforov Petr Vladimirovich – Doctor of Medicine, Oncologist, Surgeon of GBU Yakut Republican Oncology Center General Surgery Department

677000, Yakutsk, ulitsa Sverdlova, 3, k.2 

МамаеваС. Н.MamaevaS. N.

Мамаева Саргылана Николаевна – к.ф.-м.н., доцент 

Mamaeva Sargylana Nikolaevna - Candidate of Physical and Mathematical Sciences, the Associate Professor of North-Eastern Federal University named after M. K. Ammosov Physics and Technology Institute Department of General and Experimental Physics 

677000, Yakutsk, ulitsa Belinskogo, 58 

АнтоновС. Р.AntonovS. R.

Антонов  тепан Романович – к.ф.-м.н., доцент 

Antonov Stepan Romanovich – Candidate of Physical and Mathematical sciences, the Associate Professor of North-Eastern Federal University named after M. K. Ammosov Physics and Technology Institute Department of Radio Physics and Electronics

677000, Yakutsk, ulitsa Belinskogo, 58 

ПавловА. Н.PavlovA. N.

Павлов Александр Николаевич – зав. лаб. 

Pavlov Aleksandr Nikolaevich – the Head of North-Eastern Federal University named after M. K. Ammosov Physics and Technology Institute Department of Radio Physics and Electronics Laboratory

677000, Yakutsk, ulitsa Belinskogo, 58 

НиколаеваН. А.NikolaevaN. A.

Николаева Надежда Анатольевна – ассистент 

Nikolaeva Nadezhda Anatolyevna – the Assistant of North-Eastern Federal University named after M. K. Ammosov Physics and Technology Institute Department of General and Experimental Physics

677000, Yakutsk, ulitsa Belinskogo, 58 

ФГБНУ ЯНЦ КМПРоссияFGBNU “The Yakut Scientifc Center of Complex Medical Problems”Russian FederationСВФУ им. М.К. АммосоваРоссияNorth-Eastern Federal University named after M. K. AmmosovRussian FederationФГБНУ ЯНЦ КМПРоссияFGBNU “The Yakut Scientific Center of Complex Medical Problems”; North Eastern Federal University named after M. K. AmmosovRussian FederationГБУ РС(Я) «Якутский республиканский онкологический диспансер»РоссияGBU Yakut Republican Oncology CenterRussian FederationФТИРоссияNorth-Eastern Federal University named after M. K. AmmosovRussian Federation20182908202504100101Copyright © Кононова И.В., Захарова Ф.А., Кириллина М.П., Никифоров П.В., Мамаева С.Н., Антонов С.Р., Павлов А.Н., Николаева Н.А., 20252025Кононова И.В., Захарова Ф.А., Кириллина М.П., Никифоров П.В., Мамаева С.Н., Антонов С.Р., Павлов А.Н., Николаева Н.А.Kononova I.V., Zakharova F.A., Kirillina M.P., Nikiforov P.V., Mamaeva S.N., Antonov S.R., Pavlov A.N., Nikolaeva N.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://ymj.elpub.ru/jour/article/view/1193

В статье представлен обзор исследований, посвященных обнаружению папилломавируса человека в крови, и обозначены неразрешенные вопросы, вытекающие из этих исследований.

There is still no clear understanding of the human papillomavirus infecting, as well as its eliminating process from the body. It is known that cervical cancer is caused by human papillomavirus in 99 percent of cases, but only in a small number of human papillomavirus infected women leads to develop cervical cancer. At the same time, based on cytological and histological analysis of the women cervical samples, it is currently impossible to establish criteria that would indicate the malignant progression possibility. Blood, as a unique tissue with specific and nonspecific protective adaptive mechanisms, can be a source of crucial information about the human body papillomavirus infecting. The article provides an overview of the research devoted to the human papillomavirus detection in blood and identifies unresolved issues arising from these studies.

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The authors declare that there are no conflicts of interest present.