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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2018.63.21</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-1164</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИГИЕНА, САНИТАРИЯ, ЭПИДЕМИОЛОГИЯ И МЕДИЦИНСКАЯ ЭКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HYGIENE, SANITATION, EPIDEMIOLOGY AND MEDICAL ECOLOGY</subject></subj-group></article-categories><title-group><article-title>Эпидемиология острых лейкозов у детей Республики Саха (Якутия)</article-title><trans-title-group xml:lang="en"><trans-title>The acute leukemia epidemiology in children of the Sakha Republic (Yakutia)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аргунова</surname><given-names>Е. Ф.</given-names></name><name name-style="western" xml:lang="en"><surname>Argunova</surname><given-names>E. F.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аргунова Елена Филипповна – к.м.н., доцент</p></bio><bio xml:lang="en"><p>Argunova Elena Filippovna, Candidate of Medical Science</p><p>Yakutsk</p></bio><email xlink:type="simple">eargunova@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кондратьева</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Kondratiev</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Кондратьева Саргылана Афанасьевна – зав. отд.</p></bio><bio xml:lang="en"><p>Kondrateva Sargylana Afanasyevna - head of oncology department</p><p>Yakutsk</p></bio><email xlink:type="simple">gematologia@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Харабаева</surname><given-names>Е. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Kharabaeva</surname><given-names>E. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Харабаева Елена Михайловна – детский онколог</p></bio><bio xml:lang="en"><p>Kharabaeva Elena Mikhailovna - children’s oncologist of the oncology department</p><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ядреева</surname><given-names>О. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Andreeva</surname><given-names>O. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ядреева Ольга Валерьевна – гематолог</p></bio><bio xml:lang="en"><p>Yadreeva Olga Valerievna, hematologist of the oncology department</p><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Николаева</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nikolaeva</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Николаева Саргылана Афанасьевна – детский онколог</p></bio><bio xml:lang="en"><p>Nikolaeva Sargylana Afanasyevna - children’s oncologist of the oncology department</p><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Протопопова</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Protopopov</surname><given-names>N. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Протопопова Надежда Николаевна – гематолог</p></bio><bio xml:lang="en"><p>Protopopova Nadezhda Nicolaevna, hematologist of the oncology department</p><p>Yakutsk</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Алексеева</surname><given-names>С. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Alekseev</surname><given-names>S. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Алексеева Саргылана Николаевна – к.м.н., доцент</p></bio><bio xml:lang="en"><p>Alexeeva Sargilana Nikolaevna - Candidate of Medical Science</p><p>Yakutsk</p></bio><email xlink:type="simple">sargylanao@mail.ru</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евсеева</surname><given-names>С. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Evseeva</surname><given-names>S. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Евсеева Сардана Анатольевна – м.н.с.</p></bio><bio xml:lang="en"><p>Evseeva Sardana Anatolievna - candidate of medical sciences</p><p>Yakutsk</p><p>contact. phone: 89679111195</p></bio><email xlink:type="simple">sarda79@mail.ru</email><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бурцева</surname><given-names>Т. Е.</given-names></name><name name-style="western" xml:lang="en"><surname>Burtseva</surname><given-names>T. E.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Бурцева Татьяна Егоровна – д.м.н., проф.; зав. лаб.</p></bio><bio xml:lang="en"><p>Burtseva Tatyana Egorovna - doctor of medical sciences, professor; head. lab.</p><p>Yakutsk</p><p>8 (914) 294-32-44</p></bio><email xlink:type="simple">bourtsevat@yandex.ru</email><xref ref-type="aff" rid="aff-5"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Баланова</surname><given-names>В. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Balanova</surname><given-names>V. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Баланова Варвара Сергеевна – студентка 6 курса</p></bio><bio xml:lang="en"><p>Balanova Varvara Sergeyevna, 6th year student of the Pediatric Department</p><p>Yakutsk</p></bio><email xlink:type="simple">ayabalana@mail.ru</email><xref ref-type="aff" rid="aff-6"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МИ СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>MI SVFU</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>Педиатрическоий центр РБ№1-НЦМ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Pediatric Center RH # 1-NMC</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-3"><aff xml:lang="ru"><institution>МИ СВФУ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>MI SVFU</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-4"><aff xml:lang="ru"><institution>ЯНЦ КМП</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Yakut Science Center of Complex Medical Problems</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-5"><aff xml:lang="ru"><institution>МИ СВФУ; ЯНЦ КМП</institution><country>Россия</country></aff><aff xml:lang="en"><institution>MI NEFU; Yakut Science Center of Complex Medical Problems</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-6"><aff xml:lang="ru"><institution>МИ СВФУ</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical Institute of M.K. Ammosov NEFU</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>28</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>63</fpage><lpage>66</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Аргунова Е.Ф., Кондратьева С.А., Харабаева Е.М., Ядреева О.В., Николаева С.А., Протопопова Н.Н., Алексеева С.Н., Евсеева С.А., Бурцева Т.Е., Баланова В.С., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Аргунова Е.Ф., Кондратьева С.А., Харабаева Е.М., Ядреева О.В., Николаева С.А., Протопопова Н.Н., Алексеева С.Н., Евсеева С.А., Бурцева Т.Е., Баланова В.С.</copyright-holder><copyright-holder xml:lang="en">Argunova E.F., Kondratiev S.A., Kharabaeva E.M., Andreeva O.V., Nikolaeva S.A., Protopopov N.N., Alekseev S.N., Evseeva S.A., Burtseva T.E., Balanova V.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1164">https://ymj.elpub.ru/jour/article/view/1164</self-uri><abstract><p>В статье представлен анализ частотных показателей: первичной заболеваемости, смертности, при острых лейкозах у детей РС(Я) за период с 2000 по 2016 г. Показатели заболеваемости острым лейкозом, острым лимфобластным лейкозом, острым нелимфобластным лейкозом в детской популяции РС(Я) являются средними и сопоставимыми с показателями других регионов РФ. В динамике отмечается снижение летальности от лейкозов, что связано с улучшением терапии и качества сопроводительной терапии.</p></abstract><trans-abstract xml:lang="en"><p>The article presents the analysis of frequency indicators: primary morbidity, mortality in acute leukemia in children of the RS (Y) for the period from 2000 to 2016. The incidence of acute leukemia, acute lymphoblastic leukemia, acute non-lymphoblastic leukemia in children’s population of the RS (I) are average and comparable with that of other regions of the Russian Federation. In dynamics there is a decrease in mortality from leukemia and this is due to the improvement of therapy and the quality of accompanying therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лейкозы</kwd><kwd>эпидемиология</kwd><kwd>дети</kwd><kwd>Якутия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>leukemia</kwd><kwd>epidemiology</kwd><kwd>children</kwd><kwd>Yakutia</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Аргунова Е.Ф. Структура, эпидемиология и лечение злокачественных новообразовааргунова, С.А. Кондратьева, О.В. Слепцов // Сб. материалов межрегиональной науч.-практ. конф. «Актуальные вопросы клинической медицины на Севере». – Якутск, 2013. - С. 24-30. Argunova E.F. Structure, epidemiology and treatment of malignant neoplasms in children of the Sakha Republic (Yakutia) / E.F. Argunova, S.A. Kondratiev, O.V. 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