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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2023.83.09</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-116</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>МЕТОДЫ ДИАГНОСТИКИ И ЛЕЧЕНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>METHODS OF DIAGNOSIS AND TREATMENT</subject></subj-group></article-categories><title-group><article-title>Остеобластические метастазы у больного с низкодифференцированной когезивной карциномой желудка</article-title><trans-title-group xml:lang="en"><trans-title>Osteoblastic metastases in a patient with low-grade cohesive gastric carcinoma</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Макаров</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Makarov</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>МАКАРОВ Альберт Дмитриевич – к.м.н, доцент</p></bio><bio xml:lang="en"><p>MAKAROV Albert D. – Ph.D., Associate Professor of the Department of Hospital Surgery</p></bio><email xlink:type="simple">makarov_albert@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тобохов</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Tobokhov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ТОБОХОВ Александр Васильевич – д.м.н. проф.</p></bio><bio xml:lang="en"><p>TOBOKHOV Aleksandr V. – MD, Professor of the Department of Hospital Surgery</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Пестерева</surname><given-names>В. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Pestereva</surname><given-names>V. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ПЕСТЕРЕВА Вера Николаевна – врач терапевт</p></bio><bio xml:lang="en"><p>PESTEREVA Vera N. - Doctor of the Department of Therapy</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ноев</surname><given-names>Д. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Noev</surname><given-names>D. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>НОЕВ Дмитрий Дмитриевич – к.м.н.</p></bio><bio xml:lang="en"><p>NOEV Dmitriy D. – PhD</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сосина</surname><given-names>С. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Sosina</surname><given-names>S. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>СОСИНА Светлана Степановна – к.м.н., доцент</p></bio><bio xml:lang="en"><p>SOSINA Svetlana S. – PhD, Associate Professor of the Department of Propaedeutic and Faculty Therapy with Physiotherapy and Endocrinology</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Тяптиргянова</surname><given-names>Т. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Tyaptirgyanova</surname><given-names>T. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ТЯПТИРГЯНОВА Татьяна Матвеевна – д.м.н., проф.</p></bio><bio xml:lang="en"><p>YANOVA Tatyana M. – MD, Professor of the Department of Hospital Surgery</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Мединститут СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Medical Institute M.K. Ammosov NEFU</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>РБ №1- Национального центра медицины</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Republican Hospital No.1 – NCM</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2023</year></pub-date><pub-date pub-type="epub"><day>04</day><month>02</month><year>2025</year></pub-date><volume>0</volume><issue>3</issue><fpage>36</fpage><lpage>40</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Макаров А.Д., Тобохов А.В., Пестерева В.Н., Ноев Д.Д., Сосина С.С., Тяптиргянова Т.М., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Макаров А.Д., Тобохов А.В., Пестерева В.Н., Ноев Д.Д., Сосина С.С., Тяптиргянова Т.М.</copyright-holder><copyright-holder xml:lang="en">Makarov A.D., Tobokhov A.V., Pestereva V.N., Noev D.D., Sosina S.S., Tyaptirgyanova T.M.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/116">https://ymj.elpub.ru/jour/article/view/116</self-uri><abstract><p>В статье представлено клиническое наблюдение остеобластических метастазов у пациента с низкодифференцированной когезивной карциномой желудка спустя несколько лет после проведения радикальной операции. Множественные остеобластические метастазы резко ухудшают качество жизни, негативно сказываются на выживаемости и требуют необходимости своевременного комплексного обследования пациентов с данной патологией на предмет раннего выявления “немых” костных метастазов с целью улучшения отдаленных результатов лечения.</p></abstract><trans-abstract xml:lang="en"><p>The article presents a clinical observation of osteoblastic metastases in a patient with poorly cohesive gastric carcinoma after several years of radical surgery. Multiple osteoblastic metastases sharply worsen the quality of life, adversely aﬀect survival rate, and require timely comprehensive examination of patients with this pathology for early detection of “silent” bone metastases in order to improve long-term results of treatment.</p><sec><title>Study objective</title><p>Study objective: to describe a clinical case of osteoblastic metastases in poorly cohesive carcinoma.</p></sec><sec><title>Patient L</title><p>Patient L., male, 48 years, was admitted to the RH#1 - NCM Therapy Department (Yakutsk, Russia) for examination with complaints of severe general weakness, severe pain in the hip joints and both lower extremities, sacrum, intensifying during walking and lying down, decreased appetite, dyssomnia due to pain syndrome.</p><p>In the Therapy Department the patient underwent CBC, biochemical analysis of blood, instrumental research. He received symptomatic treatment: table 5 diet, Nutriﬂex 40/80 intravenously. for parenteral nutrition, omeprazole with an antiulcer purpose, tramadol 2.0 ml and diclofenac 3.0 ml for pain control, vitamins B12 200 mcg per day, ketotifen 1 mg 1 time in the evening with a sedation. The condition is unchanged, the expressed pain syndrome in the hip joints and sacrum remains.</p><p>The patient was discharged with recommendations and referred to the Yakutsk Republican Oncological Dispensary to an oncologist and a chemotherapist for the selection of eﬀective analgesic drug therapy and possible local radiation therapy.</p></sec><sec><title>Conclusion</title><p>Conclusion. Poorly cohesive gastric carcinoma is often diagnosed at late stages and has a poor prognosis. Our clinical case demonstrates that this form of cancer can be a source of multiple osteoblastic metastases, which drastically worsens the quality of life and adversely aﬀects survival rate, and requires a timely comprehensive examination of patients with this pathology for early detection of “silent” bone metastases in order to improve long-term treatment results.</p></sec></trans-abstract><kwd-group xml:lang="ru"><kwd>низкодифференцированная когезивная карцинома желудка</kwd><kwd>остеобластические метастазы</kwd><kwd>компьютерная томография</kwd><kwd>остеосцинтиграфия</kwd></kwd-group><kwd-group xml:lang="en"><kwd>poorly cohesive gastric carcinoma</kwd><kwd>osteoblastic metastases</kwd><kwd>computed tomography</kwd><kwd>bone scintigraphy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Данилова Н.В., Олейникова Н.А., Мальков П.Г. 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