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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2018.64.10</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-1106</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОРИГИНАЛЬНЫЕ ИССЛЕДОВАНИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>ORIGINAL RESEARCH</subject></subj-group></article-categories><title-group><article-title>Клиническая характеристика алкогольной болезни печени</article-title><trans-title-group xml:lang="en"><trans-title>Clinical characteristics of alcoholic liver disease</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гатилова</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Gatilova</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гатилова Марина Ильинична – аспирант </p></bio><bio xml:lang="en"><p>Gatilova Marina Ilinichna - post-graduate student of the department of propaedeutic and faculty therapy with endocrinology and exercise therapy at the medical institute</p><p>Tel.:89142873614 </p></bio><email xlink:type="simple">GatilovaMari@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Чибыева</surname><given-names>Л. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Chibyeva</surname><given-names>L. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Чибыева Людмила Григорьевна – д.м.н., проф </p></bio><bio xml:lang="en"><p>Chibyeva Lyudmila Grigoryevna - Doctor of Medical Sciences, рrofessor, Medical Institute of the M.K. Ammosov North-Eastern Federal University, рrofessor of the department of propaedeutics and Faculty Therapy with endocrinology and exercise therapy</p><p>Tel.: 89241734445 </p></bio><email xlink:type="simple">chibyeva_l@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МИ СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.K. Ammosov Northeastern Federal University</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>МИ СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.K. Ammosov North-Eastern Federal University;</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>29</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>4</issue><fpage>37</fpage><lpage>39</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Гатилова М.И., Чибыева Л.Г., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Гатилова М.И., Чибыева Л.Г.</copyright-holder><copyright-holder xml:lang="en">Gatilova M.I., Chibyeva L.G.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1106">https://ymj.elpub.ru/jour/article/view/1106</self-uri><abstract><p>Изучены особенности клинического течения алкогольной болезни печени в различных этнических группах в сравнении с хроническим алкогольно-вирусным и вирусным гепатитом В. Всем больным проведено клиническое и лабораторное обследование. Установлено, что у коренных больных хронические алкогольные гепатиты формировались в более короткие сроки, о чем свидетельствует высокая частота их выявления в возрастных группах до 20 и от 20 до 29 лет, и характеризовались более выраженными клиническими проявлениями. Основными отличительными признаками алкогольных поражений печени, независимо от наличия или отсутствия HBV-инфекции, являются гепатомегалия, превалирование выраженных внепеченочных проявлений, повышение активности АлАТ в сочетании с ГГТП, а также иммунологические сдвиги.</p></abstract><trans-abstract xml:lang="en"><p>The features of the clinical course of alcoholic liver disease in various ethnic groups were studied in comparison with chronic alcohol-viral and viral hepatitis B.</p><p>All patients underwent clinical and laboratory examination.</p><p>It was revealed that in indigenous patients chronic alcoholic hepatitis was formed in a shorter time, as evidenced by the high frequency of their detection in the age groups up to 20 and from 20 to 29 years and was characterized by more pronounced clinical manifestations.</p><p>The main distinguishing features of alcoholic liver damage, regardless of the presence or absence of CVH infection, are hepatomegaly, the prevalence of pronounced extrahepatic manifestations, increased activity of AlAT in combination with GGT, and immunological changes.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>алкогольная болезнь печени</kwd><kwd>алкогольный хронический гепатит</kwd><kwd>алкогольно-вирусный гепатит</kwd><kwd>хронический вирусный гепатит В</kwd></kwd-group><kwd-group xml:lang="en"><kwd>alcoholic liver disease</kwd><kwd>chronic alcoholic hepatitis</kwd><kwd>alcoholic viral hepatitis</kwd><kwd>chronic viral hepatitis B</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Абдурахманов Д.Т. 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