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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2018.61.28</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-1093</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>СЛУЧАЙ ИЗ ПРАКТИКИ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CLINICAL CASE</subject></subj-group></article-categories><title-group><article-title>Региональный тромболизис при массивной тромбоэмболии легочной артерии у женщины в первом триместре беременности</article-title><trans-title-group xml:lang="en"><trans-title>Regional thrombolysis with massive thromboembolism of the pulmonary artery in a woman in the first trimester of pregnancy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлев</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovlev</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Яковлев Антон Антонович – к.м.н., врач ангиохирург</p><p>Якутск</p></bio><bio xml:lang="en"><p>Yakovlev Anton Antonovich - PhD, doctor angio-surgeon</p><p>Yakutsk </p></bio><email xlink:type="simple">jakvlev.antn@rambler.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Винокуров</surname><given-names>М. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Vinokurov</surname><given-names>M. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Винокуров Михаил Михайлович – д.м.н., проф., зав. кафедрой Медицинского института</p><p>Якутск</p></bio><bio xml:lang="en"><p>Vinokurov Mikhail Mikhailovich - doctor of medical sciences, prof., Head of Department of Medical Institute</p><p>Yakutsk </p></bio><email xlink:type="simple">mmvmi@rambler.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Винокуров</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Vinokurov</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Куров Михаил Андреевич – аспирант</p><p>Якутск</p></bio><bio xml:lang="en"><p>Vinokurov Mikhail Andreevich - graduate student</p><p>Yakutsk </p></bio><email xlink:type="simple">michailwork@mail.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>РБ №2-ЦЭМП</institution><country>Россия</country></aff><aff xml:lang="en"><institution>RH №2 – Emergency Medical Centre</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>M.K. Ammosov NEFU</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>26</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>92</fpage><lpage>94</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Яковлев А.А., Винокуров М.М., Винокуров А.В., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Яковлев А.А., Винокуров М.М., Винокуров А.В.</copyright-holder><copyright-holder xml:lang="en">Yakovlev A.A., Vinokurov M.M., Vinokurov A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1093">https://ymj.elpub.ru/jour/article/view/1093</self-uri><abstract><p>В статье описан клинический пример успешно проведенного регионального тромболизиса при массивной тромбоэмболии легочной артерии у женщины при I триместре беременности. Проведенная локальная тромболизисная терапия спасла не только жизнь женщины, но и жизнь зачатого ребенка.</p></abstract><trans-abstract xml:lang="en"><p>The article describes a clinical example of successful regional thrombolysis with massive pulmonary arterial thromboembolism of the pulmonary artery of women in the first first trimester of pregnancy. Conducted local thrombolytic therapy saved not only the life of a woman, but also the life of a conceived child.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>тромбоэмболия легочной артерии</kwd><kwd>региональная тромболитическая терапия</kwd><kwd>легочная артерия</kwd><kwd>задняя большеберцовая вена</kwd><kwd>международное нормализованное отношение (МНО)</kwd><kwd>протромбиновый индекс (ПТИ)</kwd><kwd>нижняя полая вена</kwd></kwd-group><kwd-group xml:lang="en"><kwd>thromboembolism of the pulmonary artery</kwd><kwd>regional thombolytic therapy</kwd><kwd>pulmonary artery</kwd><kwd>posterior tibial vein</kwd><kwd>international normalized ratio</kwd><kwd>prothrombin index</kwd><kwd>inferior vena cava</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Российские клинические рекомендации по диагностике, лечению и профилактике венозных тромбоэмболических осложнений // Флебология.– 2010. -4:1:2:2-37.</mixed-citation><mixed-citation xml:lang="en">Russian clinical guidelines for the diagnosis, treatment and prevention of venous thromboembolic complications // Phlebology. – 2010. - 4:1:2:2-37.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Профилактика венозных тромбоэмболических осложнений в травматологии и ортопедии. 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