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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">ymj</journal-id><journal-title-group><journal-title xml:lang="ru">Якутский медицинский журнал</journal-title><trans-title-group xml:lang="en"><trans-title>Yakut Medical Journal</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1813-1905</issn><issn pub-type="epub">2312-1017</issn><publisher><publisher-name>ЯНЦ КМП</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.25789/YMJ.2018.61.13</article-id><article-id custom-type="elpub" pub-id-type="custom">ymj-1046</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ГИГИЕНА, САНИТАРИЯ, ЭПИДЕМИОЛОГИЯ И МЕДИЦИНСКАЯ ЭКОЛОГИЯ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>HYGIENE, SANITATION, EPIDEMIOLOGY AND MEDICAL ECOLOGY</subject></subj-group></article-categories><title-group><article-title>Изучение особенностей иммунитета у детей с хроническим назофарингитом</article-title><trans-title-group xml:lang="en"><trans-title>The study of immunity features in children with chronic nasopharyngitis</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Иванова</surname><given-names>О. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Ivanova</surname><given-names>O. N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Иванова Ольга Николаевна – д.м.н., проф.</p><p>Якутск</p></bio><bio xml:lang="en"><p>Ivanova Olga Nikolaevna - doctor of medical sciences, professor of Department of Pediatrics and pediatric surgery</p><p>Yakutsk </p></bio><email xlink:type="simple">olgadoctor@list.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гольдерова</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Goldirova</surname><given-names>А. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Гольдерова Айталина Семеновна – д.м.н., гл.н.с.-руковод. отдела</p><p>Якутск</p></bio><bio xml:lang="en"><p>Goldirova Аitalina Semenovna - doctor of medical sciences, chief researcher of the Department study the mechanisms of adaptation</p><p>Yakutsk </p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>МИ СВФУ им. М.К. Аммосова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>MI NEFU</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ЯНЦ КМП</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Yakut scientific center of complex medical problems</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>26</day><month>08</month><year>2025</year></pub-date><volume>0</volume><issue>1</issue><fpage>43</fpage><lpage>44</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Иванова О.Н., Гольдерова А.С., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Иванова О.Н., Гольдерова А.С.</copyright-holder><copyright-holder xml:lang="en">Ivanova O.N., Goldirova А.S.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://ymj.elpub.ru/jour/article/view/1046">https://ymj.elpub.ru/jour/article/view/1046</self-uri><abstract><p>Изучен иммунный статус у детей с хроническим назофарингитом. Выявлено, что у детей с хроническим назофарингитом снижено содержание IgA, CD25+ лимфоцитов, CD4+. Всем обследованным детям была проведена терапия препаратом ликопид 1мг в сутки в течение 10 дней, повторный курс был проведен через 1 мес. Выявлено, что терапия препаратом ликопид больных хроническим назофарингитом приводит к нормализации сниженных показателей иммунного статуса: повышению содержания СD3+ и СD25+ , увеличению концентрации IgA.</p></abstract><trans-abstract xml:lang="en"><p>Immune status was studied in children with chronic nasopharyngitis. It was revealed that in children with chronic nasopharyngitis the content of IgA, CD25 + lymphocytes, CD4 + was reduced. All examined children underwent therapy with lycopid 1 mg per day for 10 days; a second course was performed after 1 month. It was revealed that lycopid therapy in patients with chronic nasopharyngitis lead to normalization of decreased immune status indicators: an increase in CD3 + and CD25 + content, an increase in IgA concentration.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>хронический</kwd><kwd>назофарингит</kwd><kwd>дети</kwd><kwd>иммунитет</kwd><kwd>иммунокорректор</kwd></kwd-group><kwd-group xml:lang="en"><kwd>chronic nasopharyngitis</kwd><kwd>children</kwd><kwd>immunity</kwd><kwd>immunocorrector</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Ратникова Л.И. новый подход к терапии острых респираторных вирусных инфекций и гриппа/ Л.И. Ратникова, Е.А. Стенько // Поликлиника. – 2009. – № 2. – С. 70–72.</mixed-citation><mixed-citation xml:lang="en">Ratnikova L.I. New approach to treatment of acute respiratory viral infections and influenza/ L.I. Ratnikova, E.A. Sten’ko // Poliklinika. - 2009. - № 2. - P. 70–72.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Острые респираторные заболевания у детей: пособие для врачей / С.О. Ключников, О.В. Зайцева, И.М. Османов [и др.] // российский вестник перинатологии и педиатрии. – 2008. – № 3. – С. 1–36.</mixed-citation><mixed-citation xml:lang="en">Acute respiratory infections in children: manual for doctors/ S.O. Klyuchnikov, O.V. Zajceva, I.M. Osmanov [et al.] // Rossijskij vestnik perinatologii i pediatrii. - 2008. - № 3. - P. 1–36.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
